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The Effects of Epidural Analgesia on Gastrointestinal Motility in Rabbits: A Comparison of Epidural Bupivacaine with Morphine

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机构: [1]Department of Anesthesiology ChangNing district central Hospital Shanghai China
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摘要:
obiective:To examine the effects of morphine and bupivacaine epidural analgesia on gastrointestinal motlty; Methods:Thirty-two male rabbits were randomly divided into 4 groups according to the content of drugs which were given by epidural 0.4 mlkg-l. group a:saline: group b:0.1% bupivacaine; group c:0.08% morphine, group d:0.1% bupivacaine 0.08% morphine compound. 20 mlkg-1 Arat glutin was given fom the gastric tube afer 60 minutes. The length of small intestine was full of Arab glutin (Dand the whole length of small intestine(Lwere measured to determine the rate of Arab glutin motion(D/L) in 13 minutes after infusing Arab glutin. Results: The analgesia was satisfactory in group c, group b and group d than in group a(P<0.05), group d has the best result.The rate ofArab glutin motion in group d and group b were both higher than that in group a and group c(P<0. 05). Conclusion:Morphine plus bupivacaine administered in postoperative epidural analgesia can reduce opioid related side efiects and get the best analgesia.

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第一作者机构: [1]Department of Anesthesiology ChangNing district central Hospital Shanghai China
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