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Simplified, Low-Cost Method on Glucose Tolerance Testing in High-Risk Group of Diabetes, Explored by Simulation of Diagnosis.

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机构: [1]Department of Endocrinology, Tongren Hospital, 537229Shanghai Jiao Tong University School of Medicine, Shanghai, China. [2]School of Energy and Materials, 74598Shanghai Polytechnic University, Shanghai, China. [3]Shanghai Engineering Research Center of Advanced Thermal Functional Materials, 74598Shanghai Polytechnic University, Shanghai, China.
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Objective: Explore the distribution of basic characteristics of high-risk groups of diabetes; verify the practical significance and diagnostic value of the "three-point method"; layered analysis of glycated hemoglobin and glycated serum albumin, and study its value and significance in the diagnosis of diabetes mellitus, Type II and pre-diabetes mellitus, Type II.Methods: 1304 high-risk individuals with T2D in Shanghai, 529 males and 841 females with an average of (50.5 ± 15.2) years old, were examined by oral glucose tolerance test (OGTT), HbA1c and GA were determined. Process the data by Python and GraphPad; judge the diagnostic value of HbA1C, GA by ROC.Results: (1) The numbers of DM, NGT, HOG, IFG, Mild-IGT and Mid-IGT in the objects were 647, 141, 70, 4, 208 and 234 respectively. In the 43-49 age group with a higher incidence, the proportion of selected high-risk groups is low. (2) The sensitivity and specificity about "three-point method" used to determine NGT is 100% and 90.11%; to determine IGR is 75.11% and 97.32%; to determine HOG is 97.14% and 100%; to determine DM is 94.67% and 100%. (3) According to ROC judgment, it is found that these 2 did not have the function of separate diagnoses, the optimal critical point of HbA1C related to DM status is 5.95%, (P<.01); HbA1C related to IGR status is 5.75% (P<.01); of GA related to DM status is 15.25% (P<.01); GA related to IGR status is 14.95% (P<.01).

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出版当年[2021]版:
大类 | 4 区 医学
小类 | 4 区 卫生保健与服务 4 区 卫生政策与服务
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 卫生保健与服务 4 区 卫生政策与服务
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出版当年[2020]版:
Q4 HEALTH CARE SCIENCES & SERVICES Q4 HEALTH POLICY & SERVICES
最新[2023]版:
Q3 HEALTH CARE SCIENCES & SERVICES Q3 HEALTH POLICY & SERVICES

影响因子: 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

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第一作者机构: [1]Department of Endocrinology, Tongren Hospital, 537229Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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通讯机构: [1]Department of Endocrinology, Tongren Hospital, 537229Shanghai Jiao Tong University School of Medicine, Shanghai, China. [2]School of Energy and Materials, 74598Shanghai Polytechnic University, Shanghai, China. [3]Shanghai Engineering Research Center of Advanced Thermal Functional Materials, 74598Shanghai Polytechnic University, Shanghai, China. [*1]School of Energy and Materials, Shanghai Polytechnic University, 2360 Jinhai Rd, Shanghai 201209, China [*2]Department of Endocrinology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai 200336, China.
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