Prevalence and risk factors of allergic rhinitis and asthma in the southern edge of the plateau grassland region of northern China: A cross-sectional study
Background: The prevalence rates of allergic rhinitis (AR) and asthma in the border region of China may be different from those in the central region of plateau grasslands. A survey was performed to investigate the prevalence and risk factors for AR, asthma, and AR combined with asthma among adults (age > 20 years) residing in the southern border of plateau grasslands in northern China. Methods: From May to August 2018, a cross-sectional survey was completed by subjects that were selected using a cluster random sampling method. The subjects completed a questionnaire and were administered skin prick tests (SPTs). Risk factors for AR, asthma, and AR combined with asthma were examined by multivariate logistic regression analyses. Results: A total of 1815 adult subjects in the selected region completed study. The prevalence rates of physician-diagnosed AR, asthma, and AR combined with asthma were 13.9% (253), 9.8% (177), and 2.9% (52), respectively. Among the patients with AR, 20.6% were found to have concurrent asthma; among the patients with asthma, 29.4% were found to have concurrent AR. Artemisia and Humulus pollen were the most common sensitizing pollen types. Approximately 70% of subjects with AR and <30% of asthma patients were sensitized to Artemisia and Humulus pollen. Symptoms of AR and asthma mainly appeared during August. A multivariable logistic regression analysis identified sensitization pollen as an independent risk factor for both AR and AR combined with asthma (AR: OR = 16.23, 95% CI: 10.15-25.96; AR combined with asthma: OR = 6.16, 95% CI: 1.28-29.66). An age >40 years old, family history of asthma, moderate-to severe AR, adverse food reactions, and mold allergies were independent risk factors for AR combined with asthma. Conclusions: This study identified the prevalence rates of AR and asthma in the southern borders of the plateau grassland in northern China (>1500 m above sea level). Sensitization pollen is an independent risk factor for AR and AR combined with asthma.
基金：
national key specialty funding of China, Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support [ZYLX201826]; Beijing Municipal Science and Technology project [Z181100001618002]; Science and Technology Research and Development project of China national railwaygGroup Co [J2019Z603]; Beijing Municipal Administration of Hospitals incubating program [PX2020028]; Beijing Key Laboratory of Biocharacteristic Profiling for Evaluation of Rational Drug Use [2019-KF11]
第一作者机构：[1]Capital Med Univ, Beijing Shijitan Hosp, Dept Allergy, 10 Tieyi Rd, Beijing 100038, Peoples R China
通讯作者：
通讯机构：[1]Capital Med Univ, Beijing Shijitan Hosp, Dept Allergy, 10 Tieyi Rd, Beijing 100038, Peoples R China[3]Capital Med Univ, Beijing TongRen Hosp, Beijing Inst Otolaryngol, Dept Otolaryngol Head & Neck Surg,Beijing Key Lab, Beijing, Peoples R China[8]Capital Med Univ, Beijing Shijitan Hosp, Dept Otorhinolaryngol Head & Neck Surg, 10 Tieyi Rd, Beijing 100038, Peoples R China[*1]Department of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University Beijing Key Laboratory of Nasal Diseases Beijing, Institute of Otolaryngology, No. 17, Hou Gou Hu Tong, Dong Cheng District, Beijing, 100005, China[*2]Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, No.10, Tieyi Road, Haidian District, Beijing, 100038, China[*3]Department of Otorhinolaryngology Head and Neck Surgery, Beijing Shijitan Hospital, Capital Medical University No.10, Tieyi Road, Haidian District, Beijing, 100038, China
推荐引用方式(GB/T 7714)：
Ma Tingting,Chen Yanlei,Pang Yaojun,et al.Prevalence and risk factors of allergic rhinitis and asthma in the southern edge of the plateau grassland region of northern China: A cross-sectional study[J].WORLD ALLERGY ORGANIZATION JOURNAL.2021,14(7):doi:10.1016/j.waojou.2021.100537.
APA：
Ma, Tingting,Chen, Yanlei,Pang, Yaojun,Wang, Xiangdong,Dai, Deqing...&Zhang, Luo.(2021).Prevalence and risk factors of allergic rhinitis and asthma in the southern edge of the plateau grassland region of northern China: A cross-sectional study.WORLD ALLERGY ORGANIZATION JOURNAL,14,(7)
MLA：
Ma, Tingting,et al."Prevalence and risk factors of allergic rhinitis and asthma in the southern edge of the plateau grassland region of northern China: A cross-sectional study".WORLD ALLERGY ORGANIZATION JOURNAL 14..7(2021)
