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Repeatability and Reproducibility of SMTube Measurement in Dry Eye Disease Patients.

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机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University and Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing 100730, China. [2]Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beihang University and CapitalMedical University, Beijing, China.

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To evaluate the intraobserver repeatability and interobserver reproducibility of Strip Meniscometry Tube (SMTube) and determine the correlations among the SMTube measurements and other ocular examinations in dry eye disease (DED) patients.The study recruited 73 eyes of 49 DED patients. Every subject was subjected to the following five measurements sequentially: the Ocular Surface Disease Index (OSDI) questionnaire, Tear Meniscus Height (TMH) assessment, SMTube measurements, tear film breakup time (BUT) examination, and Schirmer I test (SIT). The repeatability and reproducibility of the measurements were assessed by the intraclass correlation coefficient (ICC) and the Bland-Altman analysis, and the correlations were evaluated by the Spearman rank-order correlation.The repeatability and reproducibility of the SMTube measurements were good in DED patients. The ICCs between the repeatability and reproducibility of the SMTube measurements were 0.789 and 0.741, respectively, and the Bland-Altman 95% limits of the repeatability and the reproducibility were -1.726 to 1.658 and -0.967 to 1.474, respectively (all P < 0.01). The SMTube measurements had correlations with TMH, BUT, and SIT. The Spearman rank correlation coefficients between SMTube and TMH; SMTube and Schirmer I test; and SMTube and BUT were 0.632, 0.617, and 0.653, respectively (all P < 0.01).The measurements of the SMTube may provide a novel, swift, noninvasive, and convenient approach to screen and diagnose DED with acceptable repeatability and reproducibility and specific correlations with TMH, BUT, and SIT.Copyright © 2021 Yiran Hao et al.

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出版当年[2020]版：

大类 | 4 区医学

小类 | 4 区医学：研究与实验 4 区眼科学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区眼科学

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第一作者机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University and Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing 100730, China.

通讯作者：

通讯机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University and Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing 100730, China. [2]Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beihang University and CapitalMedical University, Beijing, China.

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