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What's the role of thymus in diabetes mellitus?

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收录情况： ◇ SCIE

作者：
Dai Xianliang[1,2] * ; Hua Li[3] * ; Chen Hui[1] * ; Li Qiheng[4] * ; Chen Wansheng[2,*1] ; Liang Chun[1,*1] ;
机构： [1]Department of Cardiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China [2]Department of Pharmacy, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China [3]Department of Neurology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China [4]Department of Cardiology, Beijing Haidian Hospital, Beijing 100080, China
出处：
DOI： 10.1016/j.intimp.2023.109765
ISSN：

摘要：
Diabetes mellitus is considered as an autoimmune inflammatory and age-related disease. As an important immune organ, the thymus is involved in the immune response and inflammatory response process. Therefore, there may be a link between changes in thymus function and diabetes. Based on previous studies, we hypothesized that thymus dysfunction due to aging and other reasons leads to changes in the generation of various inflammatory-immune cells and inflammatory cytokines that regulate insulin resistance, and then participates in the development of diabetes and its complications. Therefore, thymus may be a key factor in diabetes and complications, and it may be a promising therapeutic strategy to improve the thymus function for patients with diabetes. The purpose of this review is to summarize and discuss recent advances in the influence of thymus function on diabetes, especially its potential mechanisms.Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.

基金：
This work was supported by National Natural Science Foundation of China (No. 91539118, 81611130092) and Shanghai Integrated Medicine cultivation collaborative project (ZY(2018-2020)-FWTX-1102).
语种：
外文
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PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 2 区 医学
小类 | 2 区 免疫学 2 区 药学
最新[2023]版：
大类 | 2 区 医学
小类 | 2 区 免疫学 2 区 药学
JCR分区：
出版当年[2021]版：
Q1 PHARMACOLOGY & PHARMACY Q2 IMMUNOLOGY
最新[2023]版：
Q1 PHARMACOLOGY & PHARMACY Q2 IMMUNOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者：
第一作者机构： [1]Department of Cardiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China [2]Department of Pharmacy, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China
共同第一作者：
通讯作者：
通讯机构： [1]Department of Cardiology, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China [2]Department of Pharmacy, Second Affiliated Hospital of Naval Medical University, Shanghai 200003, China [*1]Department of Cardiology, Second Affiliated Hospital of Naval Medical University, No. 415 Fengyang Road, Shanghai, China
推荐引用方式(GB/T 7714)：
Dai Xianliang,Hua Li,Chen Hui,et al.What's the role of thymus in diabetes mellitus?[J].INTERNATIONAL IMMUNOPHARMACOLOGY.2023,116:doi:10.1016/j.intimp.2023.109765.
APA：
Dai Xianliang,Hua Li,Chen Hui,Li Qiheng,Chen Wansheng&Liang Chun.(2023).What's the role of thymus in diabetes mellitus?.INTERNATIONAL IMMUNOPHARMACOLOGY,116,
MLA：
Dai Xianliang,et al."What's the role of thymus in diabetes mellitus?".INTERNATIONAL IMMUNOPHARMACOLOGY 116.(2023)

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