个人科研网厅 | | 帮助
高级检索
当前位置： 首页 > 详情页

Design, methodology, and preliminary results of the non-human primates eye study

| 认领 | 导出 | |

文献详情

资源类型：
WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Wu Jian[1,2] * ; Liu Wei[3] * ; Zhu Sirui[4] ; Liu Hongyi[1] ; Chen Kezhe[2] ; Zhu Yingting[2] ; Li Zhidong[2] ; Yang Chenlong[5] ; Pan Lijie[1] ; Li Ruyue[1] ; Lin Caixia[1] ; Tian Jiaxin[1] ; Ren Jiaoyan[3] ; Xu Liangzhi[6] ; Yu Hanxiang[6] ; Luo Fagao[6] ; Huang Zhiwei[6] ; Su Wenru[2] ; Wang Ningli[1] ; Zhuo Yehong[2] ;
机构： [1]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No. 1 Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China. [2]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-Sen University, Guangzhou, 510060, China. [3]School of Food Sciences and Engineering, South China University of Technology, Guangzhou, 510641, China. [4]Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. [5]Department of Neurosurgery, Peking University Third Hospital, Haidian District, Beijing, China. [6]Guangzhou Huazhen Biosciences, Guangzhou, 510900, China.
出处：
DOI： 10.1186/s12886-023-02796-6
ISSN：

关键词： Non-human primates Eye study Methodology Ocular parameters

摘要：
To describe the normative profile of ophthalmic parameters in a healthy cynomolgus monkey colony, and to identify the characteristic of the spontaneous ocular disease non-human primates (NHP) models.The NHP eye study was a cross-sectional on-site ocular examination with about 1,000 macaques held in Guangdong Province, southeastern China. The NHPs (Macaca fascicularis, cynomolgus) in this study included middle-aged individuals with a high prevalence of the ocular disease. The NHP eye study (NHPES) performed the information including systematic data and ocular data. Ocular examination included measurement of intraocular pressure (IOP), anterior segment- optical coherence tomography (OCT), slit-lamp examination, fundus photography, autorefraction, electroretinography, etc. Ocular diseases included measurement of refractive error, anisometropia, cataract, pterygium, etc. RESULTS: A total of 1148 subjects were included and completed the ocular examination. The average age was 16.4 ± 4.93 years. Compared to the male participants, the females in the NHPES had shorter axial length and the mean Average retinal nerve fiber layer (RNFL) thickness (except for the nasal quadrants). The mean IOP, anterior chamber depth, lens thickness, axial length, central corneal thickness, choroid thickness and other parameters were similar in each group.The NHPES is a unique and high-quality study, this is the first large macaque monkey cohort study focusing on ocular assessment along with comprehensive evaluation. Results from the NHPES will provide important information about the normal range of ophthalmic measurements in NHP.© 2023. The Author(s).

基金：
Beijing Municipal of Health Reform and Development Project, #2019–4 (Beijing, China), Capital Health Research and Development of Special (2020–2-1081), Beijing Natural Science Foundation (JQ20029), National Key R&D Project of China (2020YFA0112701), Beijing Talents Found (2016000021223ZK28), and the National Natural Science Foundation of China (82071000).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 4 区 医学
小类 | 4 区 眼科学
最新[2023]版：
大类 | 4 区 医学
小类 | 3 区 眼科学
JCR分区：
出版当年[2021]版：
Q3 OPHTHALMOLOGY
最新[2023]版：
Q3 OPHTHALMOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者：
第一作者机构： [1]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, No. 1 Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China. [2]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-Sen University, Guangzhou, 510060, China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Wu Jian,Liu Wei,Zhu Sirui,et al.Design, methodology, and preliminary results of the non-human primates eye study[J].BMC OPHTHALMOLOGY.2023,23(1):53.doi:10.1186/s12886-023-02796-6.
APA：
Wu Jian,Liu Wei,Zhu Sirui,Liu Hongyi,Chen Kezhe...&Zhuo Yehong.(2023).Design, methodology, and preliminary results of the non-human primates eye study.BMC OPHTHALMOLOGY,23,(1)
MLA：
Wu Jian,et al."Design, methodology, and preliminary results of the non-human primates eye study".BMC OPHTHALMOLOGY 23..1(2023):53

相关文献

[1]Fundus Tessellation and Parapapillary Atrophy, as Ocular Characteristics of Spontaneously High Myopia in Macaques: The Non-Human Primates Eye Study [2]Intraocular amphiregulin and axial elongation in non-human adolescent primates [3]Central corneal thickness in adult Chinese. Association with ocular and general parameters. The Beijing Eye Study [4]Prevalence of smoking and its associations with ocular parameters in adult Chinese: The Beijing Eye Study [5]Associations between Gender, Ocular Parameters and Diseases: The Beijing Eye Study [6]Lens Vaults and Their Association with Ocular and General Parameters: The Beijing Eye Study [7]Anthropomorphic measurements and general and ocular parameters in adult Chinese: the Beijing Eye Study [8]Refractive error, ocular and general parameters and ophthalmic diseases. The Beijing Eye Study [9]Discovery of clinical manifestations in spontaneous glaucoma suspect non-human primates [10]Intraocular pressure and its normal range adjusted for ocular and systemic parameters. The Beijing Eye Study 2011

资源点击量：21434 今日访问量：0 总访问量：1221 更新日期：2025-02-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学附属北京同仁医院 技术支持：重庆聚合科技有限公司 地址：北京市东城区东交民巷1号(100730)