机构：[1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China首都医科大学附属北京同仁医院研究所眼科研究所[2]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China首都医科大学附属同仁医院
Purpose: To characterize and compare clinical and immunological features of para(p)-autoimmune retinopathy (AIR) and non-para(np)-AIR and to assess the clinical significance of the presence of serum anti-retinal antibodies (ARAs).Methods: We retrospectively reviewed 48 Chinese patients with p-AIR or np-AIR who took comprehen-sive ophthalmic examinations and lab tests of the presence of serum ARAs.Results: p-AIR patients differed from np-AIR patients in terms of disease progression, ocular inflammation, findings of OCT, FFA, and presence of ARAs. No significant difference was found in the band number of serum ARAs between AIR patients and healthy controls. The prevalence of antibodies to recoverin and ?-enolase in the sera of p-AIR was significantly higher than that of the healthy individuals.Conclusion: While having many similar clinical signs, patients with p-AIR or np-AIR nevertheless dis-played unique characteristics. Detection of ARAs subtypes, rather than their quantity, may be helpful in evaluating the conditions in the verified instances.
基金：
Beijing Municipal Natural Science Foundation [7192034]; Key research program of the Beijing Institute of Ophthalmology
第一作者机构：[1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China[2]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China[*1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
共同第一作者：
通讯作者：
通讯机构：[1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China[2]Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China[*1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
推荐引用方式(GB/T 7714)：
Zeng Hui-Yang,Liu Qian,Peng Xiao-Yan,et al.Comparison of Clinical and Immunological Features of Para- and Non-Paraneoplastic Autoimmune Retinopathy in Chinese-A Series of 48 Cases[J].OCULAR IMMUNOLOGY AND INFLAMMATION.2024,32(5):664-672.doi:10.1080/09273948.2023.2193844.
APA：
Zeng, Hui-Yang,Liu, Qian,Peng, Xiao-Yan,Zhang, Zi-Jun,Cao, Kai...&Wang, Ning-Li.(2024).Comparison of Clinical and Immunological Features of Para- and Non-Paraneoplastic Autoimmune Retinopathy in Chinese-A Series of 48 Cases.OCULAR IMMUNOLOGY AND INFLAMMATION,32,(5)
MLA：
Zeng, Hui-Yang,et al."Comparison of Clinical and Immunological Features of Para- and Non-Paraneoplastic Autoimmune Retinopathy in Chinese-A Series of 48 Cases".OCULAR IMMUNOLOGY AND INFLAMMATION 32..5(2024):664-672
