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Surgical and Biochemical Outcomes in Nerve Monitored Reoperation Surgery for Recurrent Papillary Thyroid Carcinoma

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机构: [1]Department of Otolaryngology-Head and Neck Surgery, Division of Thyroid and Parathyroid Endocrine Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA. [2]Department of Thyroid Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China. [3]Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [4]Key Laboratory of Otorhinolaryngology-Head and Neck Surgery, Ministry of Education, Beijing Institute of Otorhinolaryngology, Beijing, China. [5]Department of Surgery, Keio University School of Medicine, Tokyo, Japan. [6]Division of Otolaryngology-Head and Neck Surgery, NorthShore University HealthSystem, Evanston, Illinois, USA. [7]Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. [8]Department of Surgery, Ito Hospita, Tokyo, Japan. [9]Department of Radiology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA. [10]Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
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关键词: papillary thyroid carcinoma recurrence reoperation thyroid surgery revision surgery thyroglobulin

摘要:
To study the surgical and biochemical outcomes in nerve-monitored reoperation or revision surgery for recurrent thyroid cancers.A single-center retrospective study.Tertiary center.We identified patients with recurrent papillary thyroid carcinoma (PTC) who underwent reoperation/revision surgery. Study outcomes were surgical complications frequency, recurrence, distant metastasis, and biological complete response (BCR) by comparing preoperative and postoperative thyroglobulin (Tg) levels.Out of 227 patients, 33.9% presented for ≥2 reoperation surgeries. Nineteen (8.4%) had permanent preoperative hypoparathyroidism while 22 patients (9.7%) had preoperative vocal cord paralysis (VCP). Following reoperation surgery, there were 12 cases (5.3%) of permanent hypocalcemia and no cases of unexpected postoperative VCP. BCR was achieved in 31 patients (35.2%) with complete Tg data. Mean preoperative Tg was 47.7 ng/mL and was 19.7 ng/mL postoperatively (p = .003). The cervical nodal recurrence rate after final surgery was 7.0% (n = 16).Reoperation surgery for recurrent PTC may help achieve biochemical remission regardless of age or the number of prior surgeries.© 2023 American Academy of Otolaryngology-Head and Neck Surgery Foundation.

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出版当年[2022]版:
大类 | 2 区 医学
小类 | 2 区 耳鼻喉科学 3 区 外科
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 耳鼻喉科学 3 区 外科
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出版当年[2021]版:
Q1 OTORHINOLARYNGOLOGY Q1 SURGERY
最新[2023]版:
Q1 OTORHINOLARYNGOLOGY Q1 SURGERY

影响因子: 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

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第一作者机构: [1]Department of Otolaryngology-Head and Neck Surgery, Division of Thyroid and Parathyroid Endocrine Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
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通讯机构: [1]Department of Otolaryngology-Head and Neck Surgery, Division of Thyroid and Parathyroid Endocrine Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA. [10]Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. [*1]Department of Otolaryngology–Head and Neck Surgery, Division of Thyroid and Parathyroid Endocrine Surgery, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.
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