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Vitrectomy with sulfur hexafluoride versus air tamponade for idiopathic macular hole: a retrospective study

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机构： [1]Department of Ophthalmology, Peking University People’s Hospital, Xizhimen South Street 11, Xi Cheng District, Beijing 100044, China [2]Eye Diseases and Optometry Institute, Beijing, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China [4]College of Optometry, Peking University Health Science Center, Beijing, China [5]Department of Biostatistics, Peking University Clinical Research Institute, Beijing, China

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关键词： Tamponade Gas Retinal perforations Surgery

摘要：

To evaluate the effect of room air and sulfur hexafluoride (SF6) gas in idiopathic macular hole(MH)surgery.Retrospective, interventional, and comparative study. 238 eyes with the idiopathic macular hole that underwent pars plana vitrectomy, internal limiting membrane peeling, fluid-air exchange, and 20% SF6 (SF6 group:125 eyes) or room air tamponade (air group: 113 eyes) were reviewed. The primary outcome measure was the closure rate of primary surgery.The baseline characteristics of the SF6 group and air group were comparable except for the hole size (479.90 ± 204.48 vs. 429.38 ± 174.63 μm, P = 0.043). The anatomical closure rate was 92.8% (116 / 125) with the SF6 group and 76.1% (86 / 113) with the air group (P < 0.001). A cut-off value of MH size to predict primary anatomical closure was 520 μm, which is based on the lower limit of 95% confidential interval of the MH size among the unclosed patients in the air group. There was no significant difference in anatomical closure rates between SF6 and air group (98.7% vs. 91.9%, P = 0.051) for MH ≤ 520 μm, whereas a significantly lower anatomical closure rate was shown in the air group than SF6 group (46.2% vs. 84.0%, P < 0.001) for MH > 520 μm.SF6 exhibited more effectiveness than air to achieve a good anatomical outcome for its longer tamponade when MH > 520 μm.© 2023. The Author(s).

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出版当年[2022]版：

大类 | 4 区医学

小类 | 4 区眼科学

最新[2023]版：

大类 | 4 区医学

小类 | 3 区眼科学

第一作者：

第一作者机构： [1]Department of Ophthalmology, Peking University People’s Hospital, Xizhimen South Street 11, Xi Cheng District, Beijing 100044, China [2]Eye Diseases and Optometry Institute, Beijing, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China [4]College of Optometry, Peking University Health Science Center, Beijing, China

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通讯作者：

通讯机构： [1]Department of Ophthalmology, Peking University People’s Hospital, Xizhimen South Street 11, Xi Cheng District, Beijing 100044, China [2]Eye Diseases and Optometry Institute, Beijing, China [3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China [4]College of Optometry, Peking University Health Science Center, Beijing, China

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