In the past 20 years, an increasing number of studies have advanced our understanding of the pathogenic mechanism of chronic urticaria (CU), providing new treatment options.This bibliometric study aimed to evaluate published reports of CU-related studies from a number of different angles, review the research trends of the studies, and provide future perspectives of CU.Publications related to CU from 2001-2022 were searched in the Web of Science Core Collection. The database file was imported to Excel and analysed using bibliometric software, including VOSviewer and BiblioShiny.A total of 4,452 publications of CU were included. The number of publications related to CU has increased steadily over time. The journal with the most published articles was Allergy, and the countries with the most publications were the United States, Germany, and Italy. The most productive author was Maurer Marcus from Germany. There was close co-authorship between authors and countries (and regions) across the world. Recent studies have focused more on the pathogenesis and treatment of CU. Future hotspots may include emerging biologics for treatment.This study shows the research development of CU over the past two decades, which may provide beneficial reference for publication and future trends in CU research.