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Prevalence and Associations of Peripheral Arterial Disease in China. The Beijing Eye Study

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机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China. Electronic address: yaxingw@gmail.com. [2]Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Hospital, Beijing Tongren Eye Center, Capital Medical University, Beijing, China. [3]Department of Ophthalmology, University of Cologne, Cologne, Germany. [4]Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany [5]Privatpraxis Prof Jonas und Dr Panda-Jonas, Heidelberg, Germany [6]Institute of Molecular and Clinical Ophthalmology, Basel, Switzerland [7]Singapore Eye Research Institute, Singapore.

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To explore the prevalence and associations of peripheral arterial disease (PAD) in China DESIGN: Population-based incidence estimate and cross-sectional study METHODS: The participants (n=3468) of the Beijing Eye Study underwent a detailed ophthalmological and systemic examination including assessment of the ankle-brachial index (ABI). PAD was defined by an ABI of less than 0.9.Blood pressure measurements of both arms and ankles were available for 1078 (31.1%) individuals. An ABI (mean:1.09±0.11;median:1.10;range:0.25,1.36) of <0.9 and <0.95 was found in 32/1078 participants (3.0%;95%CI:2.0,4.0) and 70/1078 individuals (6.5%;95%CI:5.0,8.0), respectively. Higher PAD prevalence (multivariable analysis) was associated with older age (odds ratio (OR):1.08;95%CI:1.02,1.15;P=0.009), lower level of education (OR:0.62;95%CI:0.43,0.90;P=0.01), lower quality of life (OR:0.67;95%CI:1.11,2.32), higher glucose serum concentration (OR:1.36;95%CI:1.09,1.58;P=0.006), lower estimated glomerular filtration rate (OR:0.98;95%CI:0.96,0.99;P=0.04), and higher prevalence of retinal vein occlusions (OR7.30;95%CI:1.63,32.6;P=0.009). PAD prevalence was not associated with the prevalence of glaucoma (P=0.53) (open-angle glaucoma:P=0.42; angle-closure glaucoma:P=0.57) and age-related macular degeneration (any AMD:P=0.39; early AMD:P=0.31; intermediate AMD:P=0.92; late AMD:P=0.99), prevalence (P=0.26) and stage (P=0.07) of diabetic retinopathy, prevalence (P=0.38) and degree (P=0.68) of nuclear cataract, prevalence (P=0.39) and degree (P=0.72) of cortical cataract, prevalence of subcapsular cataract (P=0.86), prevalence of pseudoexfoliation (P=0.65), intraocular pressure (P=0.50), axial length (P=0.56), and peripapillary retinal nerve fiber layer thickness (P=0.68).The PAD prevalence (3.0%;95%CI:2.0,4.0) was relatively low in this cohort from rural and urban Beijing, with older age, lower educational level, lower quality of life, higher glucose serum concentration, lower estimated glomerular filtration rate, and higher prevalence of retinal vein occlusions as main associated factors.Copyright © 2023. Published by Elsevier Inc.

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出版当年[2023]版：

大类 | 1 区

医学

小类 | 1 区眼科学

最新[2023]版：

大类 | 1 区

医学

小类 | 1 区眼科学

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出版当年[2022]版：

Q1 OPHTHALMOLOGY

最新[2023]版：

Q1 OPHTHALMOLOGY

影响因子： 4.1 最新[2023版] 4.4 最新五年平均 4.2 出版当年[2022版] 4.9 出版当年五年平均 5.488 出版前一年[2021版] 4.1 出版后一年[2023版]

第一作者：

第一作者机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China. Electronic address: yaxingw@gmail.com. [*1]Beijing Tongren Hospital, 1 Dongjiaomin Lane, Dongcheng, 100730, Beijing, China

通讯作者：

通讯机构： [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China. Electronic address: yaxingw@gmail.com. [*1]Beijing Tongren Hospital, 1 Dongjiaomin Lane, Dongcheng, 100730, Beijing, China

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