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Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet

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收录情况： ◇ SCIE

作者：
Cai Chunyang[1,2] * ; Ma Yingyan[1,2] * ; He Shuai[1,2] * ; Meng Chunren[1,2] ; Gu Chufeng[1,2] ; He Jiangnan[1,3] ; Lhamo Thashi[4] ; Draga Deji[4] ; Zhou Chuandi[1,2,*2] ; Qiu Qinghua[4,5,*1] ;
机构： [1]Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. [2]National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, PR China. [3]Department of Preventative Ophthalmology, Shanghai Eye Diseases Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, PR China. [4]Department of Ophthalmology, Shigatse People's Hospital, Shigatse, Tibet, PR China. [5]Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
出处：
DOI： 10.4103/IJO.IJO_1546_23
ISSN：

摘要：
This study aimed to explore the influence of high altitude on myopia, macular choroidal thickness (mCT), and macular retinal thickness (mRT) in adolescents.Two schools, one in Shanghai (at sea level) and one in Shigatse, Tibet (more than 4000 m above sea level), were selected. Refractive error was measured by an autorefractor instrument and subjective refraction, and mCT and mRT were measured at three concentric circles by optical coherence tomography. Student's t-test, Chi-square test, and multiple linear regression analyses were used to analyze the data.A total of 1114 participants (657 and 457 in Shanghai and Tibet, respectively) were enrolled in this cross-sectional study. The average age of the participants was 18.81 ± 1.10 years, and 44.34% were males. The spherical equivalent (SE) of adolescents in Shanghai was significantly lower than that of adolescents in Tibet (-4.14 ± 2.37 D and -2.12 ± 1.87 D, P < 0.01). The prevalence of myopia and high myopia among adolescents in Shanghai (94.52%, 19.48%) was significantly higher than those among adolescents in Tibet (44.74%, 2.41%) ( P < 0.01). The mCT of Tibetan adolescents was significantly thicker than that of Shanghai adolescents (295.80 ± 62.46 μm and 218.71 ± 61.42 μm, P < 0.01), especially the central mCT. The mRT of Tibetan adolescents was also thicker than that of Shanghai adolescents (301.42 ± 23.26 μm and 281.04 ± 12.24 μm, P < 0.01).Compared with Shanghai adolescents, the choroid of Tibet adolescents is thicker, and the myopia prevalence is lower. It is speculated that increased altitude is associated with the thickening of mCT and a low myopia prevalence.Copyright © 2023 Copyright: © 2023 Indian Journal of Ophthalmology.

基金：
This work was sup­ported by the National Natural Science Foundation of China under grants 81970811 and 82371072 and the Domestic Sci­ence and Technology Cooperation Project of Shanghai Mu­nicipal Science and Technology Commission under grant 21015800700.
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外文
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中科院(CAS)分区：
出版当年[2023]版：
大类 | 4 区 医学
小类 | 4 区 眼科学
最新[2023]版：
大类 | 4 区 医学
小类 | 4 区 眼科学
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出版当年[2022]版：
Q2 OPHTHALMOLOGY
最新[2023]版：
Q2 OPHTHALMOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2022版] 出版当年五年平均 出版前一年[2021版] 出版后一年[2023版]

第一作者：
第一作者机构： [1]Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. [2]National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, PR China.
共同第一作者：
通讯作者：
通讯机构： [1]Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. [2]National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai, PR China. [4]Department of Ophthalmology, Shigatse People's Hospital, Shigatse, Tibet, PR China. [5]Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. [*1]Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. [*2]Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
推荐引用方式(GB/T 7714)：
Cai Chunyang,Ma Yingyan,He Shuai,et al.Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet[J].INDIAN JOURNAL OF OPHTHALMOLOGY.2024,72(SUPPL 2):S240-S247.doi:10.4103/IJO.IJO_1546_23.
APA：
Cai Chunyang,Ma Yingyan,He Shuai,Meng Chunren,Gu Chufeng...&Qiu Qinghua.(2024).Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet.INDIAN JOURNAL OF OPHTHALMOLOGY,72,(SUPPL 2)
MLA：
Cai Chunyang,et al."Influence of high altitude on choroid thickness, retinal thickness, and myopia: A cross-sectional study comparing adolescents in Shanghai and Tibet".INDIAN JOURNAL OF OPHTHALMOLOGY 72..SUPPL 2(2024):S240-S247

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