机构：[1]Department of Cadre Physical Examination Center, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.[2]Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.江苏省人民医院[3]Department of Cardiology, Huayin People's Hospital, Weinan, Shaanxi, China.[4]Department of Cardiology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.[5]Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.[6]Department of Cardiology, The Third Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.[7]Department of Cardiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
This study was to estimate the associations of volatile organic compounds (VOCs) exposure with the prevalence of total and specific cardiovascular disease (CVD) among the general adult population. This cross-sectional study analyzed 15 urinary VOC metabolites in the general population using the 2011-2016 National Health and Nutrition Examination Survey (n = 5,213). The weighted study population with 47.0 years median age, was primarily female (51.2%). The prevalence of total CVD in the overall population was 7.9%. The single-exposure analyzes of AAMA, ATCA, CEMA, CYMA, DHBMA, 3HPMA, and 3MHA +4MHA were significantly associated with increased prevalence of total CVD. Qgcomp regression consistently showed that urinary VOCs-mixed exposure was positively correlated with the prevalence of total and specific CVDs (chronic heart failure, angina, and stroke), and highlighted each VOCs metabolite weights and direction. The similar results were observed for the WQS regression using mixed analysis methods. In conclusion, exposure to VOCs increases CVD prevalence and advances the identification of risk factors for CVD for environmental study.
基金：
The work was supported by the Science and Technology Talents Support Program of Shaanxi Provincial People’s
Hospital [No. 2021BJ-10]; Science and technology development incubation fund of Shaanxi Provincial People’s
Hospital [2022YJY-06]; Science and Technology Program of Xi’an, China [No. 23YXYJ0144]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类|4 区医学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
最新[2025]版：
大类|4 区医学
小类|4 区环境科学4 区公共卫生、环境卫生与职业卫生
JCR分区：
出版当年[2022]版：
Q3ENVIRONMENTAL SCIENCESQ3PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
第一作者机构：[1]Department of Cadre Physical Examination Center, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
共同第一作者：
通讯作者：
通讯机构：[4]Department of Cardiology, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.[6]Department of Cardiology, The Third Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.[7]Department of Cardiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.[*1]Department of Cardiology, Shaanxi Provincial People’s Hospital, 256 youyi West Road, Xi’an, Shaanxi 710000, China[*2]Department of Cardiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 XianXia Road, Shanghai 200336, China
推荐引用方式(GB/T 7714)：
Ma Meijuan,Zhu Xu,Li Feipeng,et al.Associations of urinary volatile organic compounds with cardiovascular disease among the general adult population[J].International Journal Of Environmental Health Research.2024,34(11):3876-3890.doi:10.1080/09603123.2024.2331732.
APA：
Ma Meijuan,Zhu Xu,Li Feipeng,Guan Gongchang,Hui Rutai...&Zhang Yong.(2024).Associations of urinary volatile organic compounds with cardiovascular disease among the general adult population.International Journal Of Environmental Health Research,34,(11)
MLA：
Ma Meijuan,et al."Associations of urinary volatile organic compounds with cardiovascular disease among the general adult population".International Journal Of Environmental Health Research 34..11(2024):3876-3890
