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Biosimilars for anti-VEGF treatment of macular diseases: country and region reports

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机构: [1]Head of Ophthalmology: Catholic University of Asunción School of Medicine, Asunción, Paraguay. [2]Consultant Vitreo-Retinal Surgeon: Retina Research Unit, National Eye, Colombo, Sri Lanka. [3]Ophthalmologist: Tongren Hospital, Beijing, China. [4]Deputy Director: Vision and Eye Research Institute, Faculty of Health, Medicine and Social Care, Anglia Ruskin University, UK. [5]Professor: Medical Research Foundation, Sankara Nethralaya & Indian Institute of Technology, Madras, Chennai, India. [6]Consultant Ophthalmologist, Tennent Institute of Ophthalmology, Gartnavel Hospital, Glasgow, Scotland.
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A major barrier to the treatment of macular diseases is the cost of anti-VEGF drugs. As the patents on these drugs expire, lower cost biosimilar drugs have become available. According to the World Health Organization, a biosimilar is a bio-therapeutic product which is similar in terms of quality, safety and efficacy to an already licensed (or reference) bio-therapeutic product.1 They are similar, not equal; their active ingredients are not identical to those of the reference product. The adoption of a biosimilar varies between countries due to factors such as regulatory approval, market acceptance, and health care policies.1–2 The following short reports from Latin America, Sri Lanka, and China give an insight into how the introduction of biosimilars has affected practice in these regions.

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第一作者机构: [1]Head of Ophthalmology: Catholic University of Asunción School of Medicine, Asunción, Paraguay.
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