To the Editor, Head and neck cancer (HNC) is the seventh most prevalent cancer worldwide.1 With the rapid development of medical technology in recent years, radiotherapy has become the main method for HNC. By utilizing the radiation damage effect of radiation on tumor cells, the structure of tumor cells is destroyed, thereby achieving the goal of killing tumor cells and controlling tumor lesions.2 However, in the process of radiation therapy, the patient's fear of disease and pain during treatment can stimulate negative emotions such as anxiety and depression, may affect the patient's prognosis.3 However, traditional nursing methods cannot provide systematic and targeted all-round nursing interventions, so the nursing effect of traditional nursing models on HNC is unsatisfactory.4 Currently, humanized care has a better impact in stroke patients, but there are few studies on its application effect on patients with head and neck tumors.5 This study hypothesized that humanized nursing can improve self-efficacy and help improve the psychological state of HNC patients.