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Comparison of Color Fundus Photography, Infrared Fundus Photography, and Optical Coherence Tomography in Detecting Retinal Hamartoma in Patients with Tuberous Sclerosis Complex

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收录情况： ◇ SCIE ◇ 统计源期刊 ◇ CSCD-C ◇ 中华系列

作者：

机构： [1]Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China [2]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing 100730, China [3]Department of Neurology, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China [4]Department of Radiology, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China

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关键词： Fundus Photography Hamartoma Infrared Imaging Optical Coherence Tomography Tuberous Sclerosis Complex

摘要：

Background:A sensitive method is required to detect retinal hamartomas in patients with tuberous sclerosis complex (TSC).The aim of the present study was to compare the color fundus photography,infrared imaging (IFG),and optical coherence tomography (OCT) in the detection rate of retinal hamartoma in patients with TSC.Methods:This study included 11 patients (22 eyes) with TSC,who underwent color fundus photography,IFG,and spectral-domain OCT to detect retinal hamartomas.TSC1 and TSC2 mutations were tested in eight patients.Results:The mean age of the 11 patients was 8.0 ± 2.1 years.The mean spherical equivalent was-0.55 ± 1.42 D by autorefraction with cycloplegia.In 11 patients (22 eyes),OCT,infrared fundus photography,and color fundus photography revealed 26,18,and 9 hamartomas,respectively.The predominant hamartoma was type I (55.6％).All the hamartomas that detected by color fundus photography or IFG can be detected by OCT.Conclusion:Among the methods of color fundus photography,IFG,and OCT,the OCT has higher detection rate for retinal hamartoma in TSC patients;therefore,OCT might be promising for the clinical diagnosis of TSC.

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出版当年[2015]版：

大类 | 4 区医学

小类 | 4 区医学：内科

最新[2023]版：

大类 | 3 区医学

小类 | 3 区医学：内科

JCR分区：

出版当年[2014]版：

Q3 MEDICINE, GENERAL & INTERNAL

最新[2023]版：

Q1 MEDICINE, GENERAL & INTERNAL

影响因子： 7.5 最新[2023版] 4.9 最新五年平均 1.053 出版当年[2014版] 1.082 出版当年五年平均 1.016 出版前一年[2013版] 0.957 出版后一年[2015版]

第一作者：

第一作者机构： [1]Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, Beijing 100045, China [2]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing 100730, China

通讯作者：

通讯机构： [2]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing 100730, China [*1]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China

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