A nationwide cross-sectional survey on prevalence, management and pharmacoepidemiology patterns on hypertension in Chinese patients with chronic kidney disease
Limited data are available on epidemiology and drug use in Chinese hypertensive patients with chronic kidney disease (CKD). We determined the prevalence; awareness, treatment, and control rates of hypertension; anti-hypertensive use, expenditure pattern; and factors associated with hypertension prevalence and control in Chinese patients with CKD. This was one of the largest cross-sectional surveys that enrolled 6079 CKD participants (mean age, 51.0 +/- 16.37 years) with or without hypertension from 22 centres across China. The prevalence, awareness, and treatment rates were 71.2%, 95.4%, and 93.7%, respectively. Control rates 1 and 2 (Blood pressure, BP < 140/90 and < 130/80 mmHg) were 41.1% and 15.0%, respectively. Patients were treated mostly with monotherapy (37.7%) or 2-drug antihypertensive combination (38.7%). Factors associated with prevalence of hypertension included age; smoking; body mass index; physical exercise; family history of hypertension; hyperuricaemia; and CKD. Control rate was associated with CKD stage, BP monitoring at home, and use of drug combinations. Despite high rates of awareness and treatment, the control rates are low. CKD stages 4 and 5 adversely
基金:
Bayer HealthCare PharmaceuticalsBayer AGBayer Healthcare Pharmaceuticals; Research on hypertensive nephropathy and ischaemic kidney diseases National key technology RD programme [2011BAI10B00, 2011BAI10B06]; Beijing Novartis Pharma; Bayer Healthcare Company Ltd (China)
第一作者机构:[1]Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Nephrol, Sch Med, Shanghai 200025, Peoples R China
共同第一作者:
通讯作者:
推荐引用方式(GB/T 7714):
Zhang Wen,Shi Wei,Liu Zhangsuo,et al.A nationwide cross-sectional survey on prevalence, management and pharmacoepidemiology patterns on hypertension in Chinese patients with chronic kidney disease[J].SCIENTIFIC REPORTS.2016,6:doi:10.1038/srep38768.
APA:
Zhang, Wen,Shi, Wei,Liu, Zhangsuo,Gu, Yong,Chen, Qinkai...&Chen, Nan.(2016).A nationwide cross-sectional survey on prevalence, management and pharmacoepidemiology patterns on hypertension in Chinese patients with chronic kidney disease.SCIENTIFIC REPORTS,6,
MLA:
Zhang, Wen,et al."A nationwide cross-sectional survey on prevalence, management and pharmacoepidemiology patterns on hypertension in Chinese patients with chronic kidney disease".SCIENTIFIC REPORTS 6.(2016)