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Acute kidney injury in China: a cross-sectional survey

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收录情况： ◇ SCIE

作者：
Li Yang[1,*1] * ; Guolan Xing[2] ; Li Wang[3] ; Yonggui Wu[4] ; Suhua Li[5] ; Gang Xu[6] ; Qiang He[7] ; Jianghua Chen[8] ; Menghua Chen[9] ; Xiaohua Liu[10] ; Zaizhi Zhu[11] ; Lin Yang[12] ; Xiyan Lian[13] ; Feng Ding[14] ; Yun Li[15] ; Huamin Wang[16] ; Jianqin Wang[17] ; Rong Wang[18] ; Changlin Mei[19] ; Jixian Xu[20] ; Rongshan Li[21] ; Juan Cao[22] ; Liang Zhang[23] ; Yan Wang[24] ; Jinhua Xu[25] ; Beiyan Bao[26] ; Bicheng Liu[27] ; Hongyu Chen[28] ; Shaomei Li[29] ; Yan Zha[30] ; Qiong Luo[31] ; Dongcheng Chen[32] ; Yulan Shen[33] ; Yunhua Liao[34] ; Zhengrong Zhang[35] ; Xianqiu Wang[36] ; Kun Zhang[37] ; Luojin Liu[38] ; Peiju Mao[39] ; Chunxiang Guo[40] ; Jiangang Li[41] ; Zhenfu Wang[42] ; Shoujun Bai[43] ; Shuangjie Shi[44] ; Yafang Wang[1] ; Jinwei Wang[1] ; Zhangsuo Liu[2] ; Fang Wang[3] ; Dandan Huang[4] ; Shun Wang[5] ; Shuwang Ge[6] ; Quanquan Shen[7] ; Ping Zhang[8] ; Lihua Wu[9] ; Miao Pan[10] ; Xiting Zou[11] ; Ping Zhu[12] ; Jintao Zhao[13] ; Minjie Zhou[14] ; Lin Yang[15] ; Wenping Hu[16] ; Jing Wang[17] ; Bing Liu[18] ; Tong Zhang[19] ; Jianxin Han[20] ; Tao Wen[21] ; Minghui Zhao[1] ; Haiyan Wang[1] ; ISN AKF 0by25 China Consortiums[1] ;
机构： [1]Peking University First Hospital, Beijing, China [2]The First Affi liated Hospital of Zhengzhou University, Zhengzhou, China [3]Sichuan Provincial People’s Hospital, Chengdu, China [4]The First Affi liated Hospital of Anhui Medical University, Anhui, Hefei, China [5]The First Affi liated Hospital of Xinjiang Medical University, Urumqi, China [6]Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China [7]Zhejiang Provincial People’s Hospital, Hangzhou, China [8]The First Affi liated Hospital of Zhejiang University, Hangzhou, China [9]General Hospital of Ningxia Medical University, Yinchuan, China [10]Ningde Municipal Hospital, Fujian Medical University, Ningde, China [11]Meishan City People’s Hospital, Meishan, China [12]The First College of Clinical Medical Science, China Three Gorges University, Yichang, China [13]The Second Affi liated Hospital of Kunming Medical University, Kunming, China [14]Shanghai Ninth People’s Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China [15]Jiangxi Provincial People’s Hospital, Nanchang, China [16]The Fourth Affi liated Hospital of Harbin Medical University, Harbin, China [17]Lanzhou University Second Hospital, Lanzhou, China [18]Shandong Provincial Hospital Affi liated to Shandong University, Jinan, China [19]Shanghai Changzheng Hospital, The Second Military Medical University, Shanghai, China [20]Renshou County People’s Hospital, Renshou, China [21]The Affi liated Provincial People’s Hospital of Shanxi Medical University, Taiyuan, China [22]Taixing People’s Hospital, Taixing, China [23]Ordos Central Hospital, Ordos, Inner Mongolia, China [24]Xinganmeng People’s Hospital, Wulanhaote, Inner Mongolia, China [25]Fuyang City People’s Hospital, Fuyang, Zhejiang, China [26]Ningbo Yinzhou Second Hospital, Ningbo, China [27]Zhongda Hospital, Southeast University, Nanjing, China [28]Hangzhou Hospital of Traditional Chinese Medicine, Hangzhou, China [29]The Second Hospital of Hebei Medical University, Shijiazhuang, China [30]Guizhou Provincial People’s Hospital, Guizhou Medical University, Guiyang, China [31]Peking University Shenzhen Hospital, Shenzhen, China [32]Hengxian People’s Hospital, Hengxian, China [33]Miyun County Hospital, Beijing, China [34]The First Affi liated Hospital of Guangxi Medical University, Nanning, China [35]Puer City People’s Hospital, Puer, China [36]Zoucheng City People’s Hospital, Zoucheng, China [37]Taihe Hospital of Traditional Chinese Medicine, Taihe, China [38]Shenzhen Longhua New District Central Hospital, Shenzhen, China [39]Tongren Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, China [40]Zhongwei City People’s Hospital, Zhongwei, China [41]Huaxian People’s Hospital, Huaxian, China [42]Suihua City First Hospital, Suihua, China [43]Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China [44]Qingxuxian City People’s Hospital, Qingxu, China
出处：
DOI： 10.1016/S0140-6736(15)00344-X
ISSN：

摘要：
Background Acute kidney injury (AKI) has become a worldwide public health problem, but little information is available about the disease burden in China. We aimed to evaluate the burden of AKI and assess the availability of diagnosis and treatment in China. Methods We launched a nationwide, cross-sectional survey of adult patients who were admitted to hospital in 2013 in academic or local hospitals from 22 provinces in mainland China. Patients with suspected AKI were screened out on the basis of changes in serum creatinine by the Laboratory Information System, and we reviewed medical records for 2 months (January and July) to confirm diagnoses. We assessed rates of AKI according to two identification criteria: the 2012 Kidney Disease: Improving Global Outcomes (KDIGO) AKI definition and an increase or decrease in serum creatinine by 50% during hospital stay (expanded criteria). We estimated national rates with data from the 2013 report by the Chinese National Health and Family Planning Commission and National Bureau of Statistics. Findings Of 2 223 230 patients admitted to the 44 hospitals screened in 2013, 154 950 (7.0%) were suspected of having AKI by electronic screening, of whom 26 086 patients (from 374 286 total admissions) were reviewed with medical records to confirm the diagnosis of AKI. The detection rate of AKI was 0.99% (3687 of 374 286) by KDIGO criteria and 2.03% (7604 of 374 286) by expanded criteria, from which we estimate that 1.4-2.9 million people with AKI were admitted to hospital in China in 2013. The non-recognition rate of AKI was 74.2% (5608 of 7555 with available data). Renal referral was done in 21.4% (1625 of 7604) of the AKI cases, and renal replacement therapy was done in 59.3% (531 of 896) of those who had the indications. Delayed AKI recognition was an independent risk factor for in-hospital mortality, and renal referral was an independent protective factor for AKI under-recognition and mortality Interpretation AKI has become a huge medical burden in China, with substantial underdiagnosis and undertreatment. Nephrologists should take the responsibility for leading the battle against AKI.

基金：
National 985 Project of China; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81270777]; Beijing Training Program for Talents [20110009001000002]; International Society of Nephrology Research Committee; Bethune Fund Management Committee; Fresenius Medical Care

基金编号： 81270777 20110009001000002

语种：
外文
高被引：
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2014]版：
大类 | 1 区 医学
小类 | 1 区 医学：内科
最新[2023]版：
大类 | 1 区 医学
小类 | 1 区 医学：内科
JCR分区：
出版当年[2013]版：
Q1 MEDICINE, GENERAL & INTERNAL
最新[2023]版：
Q1 MEDICINE, GENERAL & INTERNAL

影响因子： 最新[2023版] 最新五年平均 出版当年[2013版] 出版当年五年平均 出版前一年[2012版] 出版后一年[2014版]

第一作者：
第一作者机构： [1]Peking University First Hospital, Beijing, China [*1]Renal Division,Peking University First Hospital,Xicheng, Beijing, 100034, China
通讯作者：
通讯机构： [1]Peking University First Hospital, Beijing, China [*1]Renal Division,Peking University First Hospital,Xicheng, Beijing, 100034, China
推荐引用方式(GB/T 7714)：
Li Yang,Guolan Xing,Li Wang,et al.Acute kidney injury in China: a cross-sectional survey[J].LANCET.2015,386(10002):1465-1471.doi:10.1016/S0140-6736(15)00344-X.
APA：
Li Yang,Guolan Xing,Li Wang,Yonggui Wu,Suhua Li...&ISN AKF 0by25 China Consortiums.(2015).Acute kidney injury in China: a cross-sectional survey.LANCET,386,(10002)
MLA：
Li Yang,et al."Acute kidney injury in China: a cross-sectional survey".LANCET 386..10002(2015):1465-1471

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