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Intraocular Pressure Fluctuation in Patients With Primary Open-angle Glaucoma Combined With High Myopia

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收录情况： ◇ SCIE

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机构： [1]Guang’anmen Hospital, China Academy of Chinese Medical Sciences [2]Beijing Tongren Eye Center, Beijing Tongren Hospital [3]Department of Epidemiology and Biostatistics, School of Public Health and Family Medicine [4]Department of Ophthalmology, Xuan Wu Hospital, Capital Medical University, Beijing [5]Department of Anatomy, Histology and Embryology, Peking University School of Basic Medical Sciences [6]Beijing University of Chinese Medicine, Beijing, PR China.

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关键词： high-tension primary open-angle glaucoma intraocular pressure fluctuations high myopia exercise

摘要：

Purpose:To investigate whether patients with primary open-angle glaucoma combined with high myopia (POAG-HM) have short-term intraocular pressure (IOP) fluctuations at resting conditions over 24 hours and after dynamic exercise.Methods:Prospective Control Clinical Study. Eighty eyes of 80 high-tension Chinese POAG patients only on prostaglandin analog locally were categorized as per their degree of myopia (myopes 6 D or more, n=30 and between -0.76 and -5.99 D, n=29) or without myopia (n=21). Twenty-four-hour IOP fluctuations at resting conditions were observed in protocol 1, and IOP fluctuations after 10-minute exercise at 20% maximum Watt (Wmax) and followed by 5 minutes of exercise at 60% Wmax were observed in protocol 2.Results:Twenty-four-hour IOP fluctuations at resting conditions were not statistically significant among groups (P=0.58). After 10 minutes of moderate (20% Wmax) exercise, patients with POAG-HM had significant IOP decrease (3.502.76 mm Hg) over other subjects (analysis of covariance, age, as a covariate, was controlled, P=0.02). After 5 minutes of heavy (60% Wmax) exercise, patients with POAG-HM had significantly a greater postexercise IOP decrease (7.57 +/- 3.47 mm Hg) than other groups (P=0.00).Conclusions:High-tension POAG patients with high myopia on only pharmacological glaucoma therapy have significantly greater IOP fluctuations after moderate and heavy exercise and do not have greater 24-hour IOP fluctuations at resting conditions.

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出版当年[2013]版：

大类 | 4 区医学

小类 | 3 区眼科学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区眼科学

JCR分区：

出版当年[2012]版：

Q2 OPHTHALMOLOGY

最新[2023]版：

Q2 OPHTHALMOLOGY

影响因子： 2 最新[2023版] 2.1 最新五年平均 1.865 出版当年[2012版] 2.046 出版当年五年平均 1.776 出版前一年[2011版] 2.427 出版后一年[2013版]

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第一作者机构： [1]Guang’anmen Hospital, China Academy of Chinese Medical Sciences [2]Beijing Tongren Eye Center, Beijing Tongren Hospital

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通讯作者：

通讯机构： [2]Beijing Tongren Eye Center, Beijing Tongren Hospital [*1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 2 Chongwenmennei Street, Dongcheng District, Beijing 100730, PR China

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