Mometasone furoate nasal spray reduces symptoms and improves quality of life in Chinese patients with moderate to severe allergic rhinitis: a multicenter open-label study
Conclusion: mometasone furoate nasal spray (MFNS) can reduce the symptoms and improve quality of life in Chinese patients with moderate to severe allergic rhinitis (AR). Objective: To evaluate the effects of MF on symptoms and quality of life in Chinese patients with moderate to severe AR. Patients and methods: In a multicenter and open-label study, 500 patients with moderate to severe AR were enrolled and received MFNS 200 mu g once daily. We visited the patients four times (at baseline, and week 1, 2, and 4) to record symptom scores and the influence of AR on daytime activities and quality of sleep. The Mini Rhinoconjunctivitis Quality of Life Questionnaire (Mini-RQLQ) and the Nocturnal Rhinoconjunctivitis Quality of Life Questionnaire (NRQLQ) were used in this study. Results: Compared with the baseline, MFNS significantly reduced the total and individual symptom scores and nocturnal sleep and daytime activities scores at week 1, 2, and 4 according to the Mini-RQLQ and NRQLQ.
基金：
Science Research for the 11th Five-year planNational Key Technology R&D Program [2007BAI18B15]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30872846, 2007CB516706]; Program for New Century Excellent Talents in UniversityProgram for New Century Excellent Talents in University (NCET) [NCET-0600185]; Schering-Plough China
第一作者机构：[1]Capital Med Univ, Beijing Inst Otolaryngol, Beijing TongRen Hosp,Key Lab Otolaryngol Head & N, Dept Otolaryngol Head & Neck Surg,Minist Educ, Beijing 100005, Peoples R China
共同第一作者：
通讯作者：
通讯机构：[1]Capital Med Univ, Beijing Inst Otolaryngol, Beijing TongRen Hosp,Key Lab Otolaryngol Head & N, Dept Otolaryngol Head & Neck Surg,Minist Educ, Beijing 100005, Peoples R China[*1]Beijing Institute of Otolaryngology, 17, HouGouHuTong, DongCheng District, Beijing 100005, China
推荐引用方式(GB/T 7714)：
Zhang Luo,Xu Geng,Wang Xiangdong,et al.Mometasone furoate nasal spray reduces symptoms and improves quality of life in Chinese patients with moderate to severe allergic rhinitis: a multicenter open-label study[J].ACTA OTO-LARYNGOLOGICA.2009,129(12):1463-1468.doi:10.3109/00016480902856570.
APA：
Zhang, Luo,Xu, Geng,Wang, Xiangdong,Liu, Shixi,Li, Yuan...&han, Demin.(2009).Mometasone furoate nasal spray reduces symptoms and improves quality of life in Chinese patients with moderate to severe allergic rhinitis: a multicenter open-label study.ACTA OTO-LARYNGOLOGICA,129,(12)
MLA：
Zhang, Luo,et al."Mometasone furoate nasal spray reduces symptoms and improves quality of life in Chinese patients with moderate to severe allergic rhinitis: a multicenter open-label study".ACTA OTO-LARYNGOLOGICA 129..12(2009):1463-1468
