机构：[1]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China[2]Rehabilitation Administration Department, National Institute of Hospital Administration, Chinese National Health and Family Planning Commission, Beijing, China[3]Centre for Eye Research Australia Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, Australia[4]Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China
Purpose To describe the prevalence of age-related macular degeneration (AMD) among older adults in rural southern mainland China. Methods Eligible persons aged 50 years or over were identified by geographically defined cluster sampling from Yangxi County, Guangdong Province, China. Participants underwent a standardised interview and comprehensive eye examinations from August to November in 2014. Digital retinal photographs were graded for AMD lesions using the Clinical Classification of Age-Related Macular Degeneration developed by the Beckman Initiative for Macular Research Classification Committee. Age-standardised prevalence of AMD and AMD lesions was calculated using the 2010 world population data and compared with those of other populations. Results Of 5825 subjects who participated (90.7% response rate), 4881 (83.8%) had fundus photographs gradable for AMD. Early, intermediate and late AMD were present in 2003 (41.0%), 879 (18.0%) and 42 (0.86%) participants. The age-standardised prevalence of early, intermediate and late AMD was 40.4% (95% CI 39.6% to 41.2%), 17.6% (95% CI 17.0% to 18.2%) and 0.79% (95% CI 0.65% to 0.95%), respectively. Total AMD was more prevalent in men than in women (62.8% vs 57.1%). Conclusions AMD is an important public health concern for rural southern China, and the prevalence of AMD was higher in men than in women.
基金：
National Institute of Hospital
Administration, Chinese National Health and Family Planning Commission
under ORBIS International North Asia (Beijing, China) contract no 1541. MH
receives support from Fundamental Research Funds of the State Key Laboratory
in Ophthalmology, Science and Technology Planning Project of Guangdong
Province 2013B20400003. MH receives support from the University of Melbourne
at Research Accelerator Program and the CERA Foundation.
第一作者机构：[1]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China
通讯作者：
通讯机构：[1]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China[3]Centre for Eye Research Australia Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, Australia[4]Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing, China[*1]Chinese Academy of Medical Sciences, Peking Union Medical College Hospital , #1 Dongjiaomin Street, Dongcheng District, Beijing 100730, China[*2]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, #54 Xianlie South Road, Yuexiu District, Guangzhou 510060, People’s Republic of China
推荐引用方式(GB/T 7714)：
Jin Guangming,Ding Xiaohu,Xiao Wei,et al.Prevalence of age-related macular degeneration in rural southern China: the Yangxi Eye Study[J].BRITISH JOURNAL OF OPHTHALMOLOGY.2018,102(5):625-630.doi:10.1136/bjophthalmol-2017-310368.
APA：
Jin, Guangming,Ding, Xiaohu,Xiao, Wei,Xu, Xiao,Wang, Lanhua...&He, Mingguang.(2018).Prevalence of age-related macular degeneration in rural southern China: the Yangxi Eye Study.BRITISH JOURNAL OF OPHTHALMOLOGY,102,(5)
MLA：
Jin, Guangming,et al."Prevalence of age-related macular degeneration in rural southern China: the Yangxi Eye Study".BRITISH JOURNAL OF OPHTHALMOLOGY 102..5(2018):625-630
