机构：[1]Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050首都医科大学附属北京友谊医院[2]Key Laboratory of Otolaryngology, Head and Neck Surgery, Ministry of Education[3]Departments of Otolaryngology, Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University, Beijing 100730首都医科大学附属北京同仁医院首都医科大学附属同仁医院[4]Diagnostic Ultrasound Beijing Tongren Hospital,Capital Medical University, Beijing 100730首都医科大学附属北京同仁医院首都医科大学附属同仁医院[5]Pathology, Beijing Tongren Hospital,Capital Medical University, Beijing 100730首都医科大学附属北京同仁医院首都医科大学附属同仁医院[6]Department of Otolaryngology, Head and Neck Surgery, Fuxing Hospital,Capital Medical University, Beijing 100038, P.R. China
Carotid body tumors (CBTs) are a rare type of extra-adrenal paraganglioma, which originate from the carotid body. A 29-year-old woman was admitted to the Department of Head and Neck Surgery, Beijing Tongren Hospital (Capital Medical University, Beijing, China) with hoarseness of the throat, which had progressively worsened over seven months. The patient had a family history of CBTs. Computed tomography and ultrasound imaging revealed multiple well-enhanced masses located at the bilateral carotid bifurcation and in the left parapharyngeal space. Surgery and pathological examination confirmed that the patient had developed regional lymph node metastasis. Significantly enhanced multiple pulmonary and hepatic lesions indicated that the patient had also developed distal metastasis. A genetic analysis performed on the family members of the patient revealed that the family carried a mutated succinate dehydrogenase D gene. In the present study, a systemic review of the literature indicated that extra vigilance is required in familial forms of CBT, in order to increase the standard of treatment for CBT patients.
基金：
China National Natural Fund Director Fund [81470123]; Beijing Municipal Science and Technology Commission 'Leading Talent' Project from the Beijing Scholars Program [(2015) 160, 141107001514002]; China Scholarship CouncilChina Scholarship Council [201508110233]
第一作者机构：[1]Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050
共同第一作者：
通讯作者：
通讯机构：[1]Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050[*1]Department of Radiology, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Beijing 100050, P.R. China
推荐引用方式(GB/T 7714)：
Lv Han,Chen Xiaohong,Zhou Shuai,et al.Imaging findings of malignant bilateral carotid body tumors: A case report and review of the literature[J].ONCOLOGY LETTERS.2016,11(4):2457-2462.doi:10.3892/ol.2016.4227.
APA：
Lv, Han,Chen, Xiaohong,Zhou, Shuai,Cui, Suping,Bai, Yunlong&Wang, Zhenchang.(2016).Imaging findings of malignant bilateral carotid body tumors: A case report and review of the literature.ONCOLOGY LETTERS,11,(4)
MLA：
Lv, Han,et al."Imaging findings of malignant bilateral carotid body tumors: A case report and review of the literature".ONCOLOGY LETTERS 11..4(2016):2457-2462
