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Explicit Filtering Based Low-Dose Differential Phase Reconstruction Algorithm with the Grating Interferometry

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机构: [1]Tsinghua Univ, Minist Educ, Key Lab Particle & Radiat Imaging, Beijing 100084, Peoples R China [2]Tsinghua Univ, Dept Engn Phys, Beijing 100084, Peoples R China [3]Capital Med Univ, Beijing Tongren Hosp, Dept Radiol, Beijing 100730, Peoples R China [4]Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing 100050, Peoples R China
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X-ray grating interferometry offers a novel framework for the study of weakly absorbing samples. Three kinds of information, that is, the attenuation, differential phase contrast (DPC), and dark-field images, can be obtained after a single scanning, providing additional and complementary information to the conventional attenuation image. Phase shifts of X-rays are measured by the DPC method; hence, DPC-CT reconstructs refraction indexes rather than attenuation coefficients. In this work, we propose an explicit filtering based low-dose differential phase reconstruction algorithm, which enables reconstruction from reduced scanning without artifacts. The algorithm adopts a differential algebraic reconstruction technique (DART) with the explicit filtering based sparse regularization rather than the commonly used total variation (TV) method. Both the numerical simulation and the biological sample experiment demonstrate the feasibility of the proposed algorithm.

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出版当年[2014]版:
大类 | 4 区 生物
小类 | 4 区 数学与计算生物学
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出版当年[2013]版:
Q3 MATHEMATICAL & COMPUTATIONAL BIOLOGY
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第一作者机构: [1]Tsinghua Univ, Minist Educ, Key Lab Particle & Radiat Imaging, Beijing 100084, Peoples R China [2]Tsinghua Univ, Dept Engn Phys, Beijing 100084, Peoples R China
通讯作者:
通讯机构: [1]Tsinghua Univ, Minist Educ, Key Lab Particle & Radiat Imaging, Beijing 100084, Peoples R China [2]Tsinghua Univ, Dept Engn Phys, Beijing 100084, Peoples R China
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