The curative effect of CO2 laser in treatment of glottic carcinoma has been focused on for a long time. The oncologic results were based on the comparison with conventional methods, survival rate and laryngeal function outcome. Data in the past literature produced convincing evidence that endoscopic surgery with CO2 laser can be considered as a valid altemative to radiotherapy and open neck surgery (larynfissure cordectomy, vertical partial laryngectomy, etc). The 5-year survival rate reached 85% - 100%.1-3 Its curative effect and advantages. have been approved by many specialists. This method has not been used widely and retrospective analysis for the large-scale clinical trials has not been reported so far. The aim of this study was to retrospectiely evaluate the oncologic results in patients with glottic carcinoma, determine the aplication and complication of CO2 laser treatment, and analyze coherent factors affecting curative effect and summarize treatment experience.