机构：[1]Department of Rehabilitation Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China[2]School of Rehabilitation Science and Institute of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
Objective To investigate the clinical effects of the mirror neuron system (MNS)-based training on upper extremity motor function and cognitive function in stroke patients. Methods Sixty stroke patients (time from stroke onset 3-9 months) with upper extremity paresis (Brunnstrom stage II-IV) and cognitive impairment (MoCA score >= 15) were enrolled in this study. Patients were randomly allocated into MNS treatment group (N = 30) and control group (N = 30). Both groups underwent regular training for upper extremity motor function and cognitive function, and the MNS group was trained with a therapeutic apparatus named mirror neuron system training (MNST) including different levels of action observation training (AOT). Training lasted 20 min/day, 5 days/week for 8 weeks. MoCA, reaction time, and Wisconsin Card Sorting Test (WCST) were assessed at baseline and 8 weeks after training. Furthermore, Fugl-Meyer assessment (FMA) and Modified Barthel index (MBI) were adopted to evaluated upper extremity motor function and daily life ability. Results After 8 consecutive weeks' training, both groups showed significant improvements on the upper extremity motor function, cognitive function, and daily life ability score after training (p < .05). The MNS group showed significantly improved upper extremity motor function and cognitive function (p < .05) compared with control group. Conclusions Combining MNS-based and conventional training can improve upper extremity motor function and cognitive function in stroke patients.
基金：
Commission of Health and Family Planning in Changning District [20164Y002]
第一作者机构：[1]Department of Rehabilitation Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
通讯作者：
通讯机构：[1]Department of Rehabilitation Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China[2]School of Rehabilitation Science and Institute of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China[*1]Department of Rehabilitation Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.[*2]School of Rehabilitation Science and Institute of Rehabilitation Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
推荐引用方式(GB/T 7714)：
Mao Huiwen,Li Yan,Tang Li,et al.Effects of mirror neuron system-based training on rehabilitation of stroke patients[J].BRAIN AND BEHAVIOR.2020,10(8):doi:10.1002/brb3.1729.
APA：
Mao, Huiwen,Li, Yan,Tang, Li,Chen, Ye,Ni, Jiawei...&Shan, Chunlei.(2020).Effects of mirror neuron system-based training on rehabilitation of stroke patients.BRAIN AND BEHAVIOR,10,(8)
MLA：
Mao, Huiwen,et al."Effects of mirror neuron system-based training on rehabilitation of stroke patients".BRAIN AND BEHAVIOR 10..8(2020)
