机构：[1]Pancreas Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China江苏省人民医院[2]Department of Hepatobiliary Surgery, Lianyungang Second People’s Hospital, Lianyungang, China[3]Department of General Surgery, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing, China[4]Department of General Surgery, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China江苏省人民医院
Objective Pancreatic cancer is a kind of high malignant tumor with a poor prognosis. The aim is to determine whether the dilated bile duct can be used to reconstruct the vessels. Methods An animal model of jugular vein and portal vein reconstruction was established using the bile duct. A total of 20 landrace pigs were selected to undergo jugular vein reconstruction or portal vein reconstruction using the bile duct as a patch or bridge. The patency was evaluated by color Doppler, the reconstructed segments were removed and examined macroscopically and histologically at specified intervals, and the results were compared with synthetic vessels (IMPRA straight, 10s03-19). Results The lumen was patent, although a low level thrombosis was observed when jugular or portal vein patching was used. For bridging, stenosis of the lumen was observed, and necrosis appeared when the bile duct was used for bridging, indicating that it is feasible to reconstruct the jugular vein and portal vein with a bile duct patch. However, the bridge was not feasible possibly due to loss of blood supply, and consequent necrosis and fibrosis. Conclusion The bile duct is technically feasible, but the outcomes are unsatisfactory.
基金：
National Natural
Science Foundation of China (No. 81372657 and No.
81572381).
第一作者机构：[1]Pancreas Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China[2]Department of Hepatobiliary Surgery, Lianyungang Second People’s Hospital, Lianyungang, China
共同第一作者：
通讯作者：
通讯机构：[1]Pancreas Center, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China[*1]The First Affiliated Hospital with Nanjing Medical University, No. 300 Guangzhou Road, Nanjing 210029, China.
推荐引用方式(GB/T 7714)：
Fan Ji-Long,Lu Cheng,Dai Xing-Long,et al.Feasibility of bile duct as venous graft for venous reconstruction in pancreatic surgery: An animal experimental study[J].VASCULAR.2020,28(4):450-456.doi:10.1177/1708538120902653.
APA：
Fan, Ji-Long,Lu, Cheng,Dai, Xing-Long,Liu, Xian,Ma, Hao...&Gao, Wen-Tao.(2020).Feasibility of bile duct as venous graft for venous reconstruction in pancreatic surgery: An animal experimental study.VASCULAR,28,(4)
MLA：
Fan, Ji-Long,et al."Feasibility of bile duct as venous graft for venous reconstruction in pancreatic surgery: An animal experimental study".VASCULAR 28..4(2020):450-456
