Background: Head and neck haemangiomas in the pharynx and larynx are rare, and the injection of bleomycin is currently one of the effective treatments. However, data on the therapeutic efficacy of this treatment are scarce. Objectives: To evaluate the clinical efficacy of bleomycin injection in the treatment of laryngopharyngeal haemangioma in adults and determine factors affecting efficacy. Materials and Methods: The clinical data of 42 adult patients with laryngopharyngeal haemangioma treated by intralesional bleomycin injection were retrospectively analysed to evaluate the clinical efficacy. Two groups (haemangioma reduction <50% and haemangioma reduction >= 50%) were compared to analyse factors affecting efficacy. Results: Seventy-five injections were administered to 42 patients: 34 (34/42 81%) patients with a haemangioma reduction >= 50% and 8 (8/42 19%) with a haemangioma reduction <50%. There was no difference in age, sex, haemangioma shape or number of operations between the two groups, but there was a significant difference in the base area of the haemangioma.
基金:
Beijing Natural Science FoundationBeijing Natural Science Foundation [7182036]; National Key Research and Development Program of China [2017YFC0112500]
第一作者机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, 1 Dongjiaominxiang, Beijing 100730, Peoples R China[2]Qingdao Univ, Dept Otolaryngol Head & Neck Surg, Affiliated Yantai Yuhuangding Hosp, Yantai, Peoples R China
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, 1 Dongjiaominxiang, Beijing 100730, Peoples R China[*1]Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, No. 1 Dongjiaominxiang, Beijing 100730, China
推荐引用方式(GB/T 7714):
Liu Feifei,Xiao Yang,Wang Jun.Therapeutic efficacy of intralesional bleomycin injection for laryngopharyngeal haemangioma in adults[J].ACTA OTO-LARYNGOLOGICA.2019,139(12):1117-1121.doi:10.1080/00016489.2019.1667528.
APA:
Liu, Feifei,Xiao, Yang&Wang, Jun.(2019).Therapeutic efficacy of intralesional bleomycin injection for laryngopharyngeal haemangioma in adults.ACTA OTO-LARYNGOLOGICA,139,(12)
MLA:
Liu, Feifei,et al."Therapeutic efficacy of intralesional bleomycin injection for laryngopharyngeal haemangioma in adults".ACTA OTO-LARYNGOLOGICA 139..12(2019):1117-1121