机构：[1]Department of Ophthalmology, Peking University People’s Hospital, Xizhimen South Street 11, Beijing 100044, China[2]Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China[3]Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing Tongren Hospital, Beijing, China首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Purpose To report a case series of three patients with intractable uveal effusion syndrome (UES), treated with partial thickness sclerectomy and intravitreal anti-VEGF therapy. Methods Three patients with intractable UES were included. All patients underwent intravitreal anti-VEGF therapy to facilitate resolution of uveal effusion. The concentrations of IL-1 beta, IL-6, IL-8, IL-10, IL-12p70, TNF and VEGF in aqueous humor were measured. Results After the last intravitreal injection, all three eyes had total resolution of the chorioretinal detachment or subretinal fluid. One eye experienced improvement in visual acuity. All patients were free from recurrence during the follow-up period. Aqueous IL-6, IL-8 and VEGF concentrations were elevated in all cases. Conclusions Our current data provided the evidence that VEGF was increased in eyes with intractable UES and anti-VEGF therapy was effective, suggesting that partial thickness sclerectomy and intravitreal anti-VEGF therapy could be a new choice for intractable UES.
第一作者机构：[1]Department of Ophthalmology, Peking University People’s Hospital, Xizhimen South Street 11, Beijing 100044, China[2]Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China[3]Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing Tongren Hospital, Beijing, China
通讯作者：
通讯机构：[1]Department of Ophthalmology, Peking University People’s Hospital, Xizhimen South Street 11, Beijing 100044, China[2]Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
推荐引用方式(GB/T 7714)：
Jing Guo,Xiaoguang Cao,Xiaoxin Li.Partial thickness sclerectomy and intravitreal anti-VEGF therapy for intractable uveal effusion syndrome[J].INTERNATIONAL OPHTHALMOLOGY.2019,39(8):1885-1890.doi:10.1007/s10792-018-0992-1.
APA：
Jing Guo,Xiaoguang Cao&Xiaoxin Li.(2019).Partial thickness sclerectomy and intravitreal anti-VEGF therapy for intractable uveal effusion syndrome.INTERNATIONAL OPHTHALMOLOGY,39,(8)
MLA：
Jing Guo,et al."Partial thickness sclerectomy and intravitreal anti-VEGF therapy for intractable uveal effusion syndrome".INTERNATIONAL OPHTHALMOLOGY 39..8(2019):1885-1890
