机构：[1]Department of Gastroenterology, Beijing Tongren Hospital, Capital Medical University, Beijing,首都医科大学附属北京同仁医院临床科室消化内科[2]Department of Gastroenterology, Xian XD Group Hospital, Xi’an, Shaanxi Province, China.
To analyze the association between non-alcoholic fatty liver disease (NAFLD) and the presence of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM). Total 411 T2DM patients were divided into NAFLD and control groups. NAFLD was diagnosed by ultrasound. Retinopathy was diagnosed by fundus photography. All patients were screened based on medical history, physical examinations, and laboratory measurements. The prevalence of NAFLD and DR in T2DM patients was 60.8% and 40.9%, respectively. The presence of DR was associated with diabetes duration, systolic blood pressure (SBP), glycated hemoglobin (HbA1c), and proteinuria (all P<.001) using univariate and multivariate regression analyses. The prevalence of DR was lower in patients with NAFLD than those without NAFLD (37.2% vs 46.6%, P=.065), and significantly lower in patients with moderate and severe NAFLD (30.2% vs 46.6%, P=.012; 14.3% vs 46.6%, P=.024). The presence of DR in NAFLD patients was associated with diabetes duration (P=.032) in Chi-squared analysis. NAFLD and DR were highly prevalent in T2DM patients. Diabetes duration, SBP, HbA1c, and proteinuria were risk factors for DR in T2DM patients. The presence of DR was lower in T2DMpatients with NAFLD, which was mainly due to their shorter diabetes duration.
基金：
This research was supported by the National Natural Science Foundation of
China (NO: 81570515).
第一作者机构：[1]Department of Gastroenterology, Beijing Tongren Hospital, Capital Medical University, Beijing,[2]Department of Gastroenterology, Xian XD Group Hospital, Xi’an, Shaanxi Province, China.
共同第一作者：
通讯作者：
通讯机构：[1]Department of Gastroenterology, Beijing Tongren Hospital, Capital Medical University, Beijing,[*1]Department of Gastroenterology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China[*2]Department of Gastroenterology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
推荐引用方式(GB/T 7714)：
Zhang Meng,Li Li,Chen Jing,et al.Presence of diabetic retinopathy is lower in type 2 diabetic patients with non-alcoholic fatty liver disease[J].MEDICINE.2019,98(18):doi:10.1097/MD.0000000000015362.
APA：
Zhang, Meng,Li, Li,Chen, Jing,Li, Bei,Zhan, Yutao&Zhang, Chuan.(2019).Presence of diabetic retinopathy is lower in type 2 diabetic patients with non-alcoholic fatty liver disease.MEDICINE,98,(18)
MLA：
Zhang, Meng,et al."Presence of diabetic retinopathy is lower in type 2 diabetic patients with non-alcoholic fatty liver disease".MEDICINE 98..18(2019)
