机构:[1]Univ Calif San Francisco, Dept Ophthalmol, San Francisco Med Sch, San Francisco, CA 94143 USA[2]Capital Med Univ, Beijing Key Lab Ophthalmol & Visual Sci, Beijing Tongren Hosp, Beijing Tongren Eye Ctr,Beijing Inst Ophthalmol, Beijing, Peoples R China研究所眼科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院[3]Capital Med Univ, Beijing Shijitan Hosp, Dept Urol, Beijing, Peoples R China
PURPOSE: To investigate the prevalence of normal-tension glaucoma (NTG) in the Chinese population through systematic review and meta-analysis. DESIGN: Systematic review and meta-analysis. METHODS: All Chinese population-based studies that reported the prevalence of NTG were identified. We searched PubMed and Chinese databases including Wanfang, China National Knowledge Infrastructure, and VIP for studies published before December 31, 2017. Random effects meta-analysis was conducted to estimate the pooled prevalence of NTG. RESULTS: Twelve studies were included in this review and meta-analysis, including 9 population-based studies and 3 studies from glaucoma clinics and managed care networks. The 9 population-based studies included a total of 30,892 subjects with 498 patients with primary open-angle glaucoma (POAG) and 354 patients with NTG. The prevalence of estimated NTG ranged from 0.36% to 1.98% and the percentage of NTG among POAG ranged from 51.43% to 83.58%. In the glaucoma clinic and managed care network studies, NTG prevalence was much lower. The overall pooled proportion of NTG among POAG in the Chinese population was 70.0% (95% confidence interval [CI] 62.0-77.0%). The overall pooled prevalence of POAG and NTG was 2.0% (95% CI 1.0-2.0%) and 1.0% (95% CI 1.01.0%), respectively. For the meta-regression of the NTG/POAG proportion, we found that age, gender, intraocular pressure, and China versus not China were not significantly associated with NTG/POAG prevalence, although the proportional prevalence decreased with increasing age category. CONCLUSIONS: In this systematic review, we found that NTG is common among patients with POAG in the Chinese population. Our findings can help guide future glaucoma studies and public health guidelines in the Chinese population. (C) 2018 Elsevier Inc. All rights reserved.
基金:
CHINA SCHOLARSHIP COUNCILChina Scholarship Council [201708110203]; THAT MAN MAY SEE, INC.; Research to Prevent BlindnessResearch to Prevent Blindness (RPB); National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [EY-002162]; NATIONAL EYE INSTITUTEUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Eye Institute (NEI) [P30EY002162] Funding Source: NIH RePORTER
第一作者机构:[1]Univ Calif San Francisco, Dept Ophthalmol, San Francisco Med Sch, San Francisco, CA 94143 USA[2]Capital Med Univ, Beijing Key Lab Ophthalmol & Visual Sci, Beijing Tongren Hosp, Beijing Tongren Eye Ctr,Beijing Inst Ophthalmol, Beijing, Peoples R China
通讯作者:
通讯机构:[1]Univ Calif San Francisco, Dept Ophthalmol, San Francisco Med Sch, San Francisco, CA 94143 USA[*1]Univ Calif San Francisco, Dept Ophthalmol, Koret Vis Ctr, 10 Koret Way, San Francisco, CA 94143 USA
推荐引用方式(GB/T 7714):
Zhao Jing,Solano Marisse Masis,Oldenburg Catherine E.,et al.Prevalence of Normal-Tension Glaucoma in the Chinese Population: A Systematic Review and Meta-Analysis[J].AMERICAN JOURNAL OF OPHTHALMOLOGY.2019,199:101-110.doi:10.1016/j.ajo.2018.10.017.
APA:
Zhao, Jing,Solano, Marisse Masis,Oldenburg, Catherine E.,Liu, Tianshu,Wang, Yaxing...&Lin, Shan C..(2019).Prevalence of Normal-Tension Glaucoma in the Chinese Population: A Systematic Review and Meta-Analysis.AMERICAN JOURNAL OF OPHTHALMOLOGY,199,
MLA:
Zhao, Jing,et al."Prevalence of Normal-Tension Glaucoma in the Chinese Population: A Systematic Review and Meta-Analysis".AMERICAN JOURNAL OF OPHTHALMOLOGY 199.(2019):101-110