The long-time paradoxical situation of non-coding RNAs (ncRNAs) has been terminated for they emerge as executive at full spectrum of gene expression and translation. More recently, it has been demonstrated that some ncRNAs apparently are associated with chemotherapy, causing cardiotoxicity, which taint long-term recovery of patients in growing body of evidence. The current review focused on up-to-date knowledge on regulation change and molecular signaling of ncRNAs, at mean time evaluate their potentials as diagnostic biomarkers or therapeutic targets to monitor and protect cardio function.
基金:
Health and Family Planning Commission Project of Shanghai [201540302]
第一作者机构:[1]Shanghai Jiao Tong Univ, Shanghai Tongren Hosp, Dept Oncol, Sch Med, Shanghai 200336, Peoples R China
通讯作者:
通讯机构:[1]Shanghai Jiao Tong Univ, Shanghai Tongren Hosp, Dept Oncol, Sch Med, Shanghai 200336, Peoples R China[*1]Department of Oncology, Shanghai Tongren Hospital, Shanghai Jiaotong University, Shanghai, 200336, China.[*2]Department of Oncology, Shanghai Tongren Hospital, Shanghai Jiaotong University, Shanghai, 200336, China
推荐引用方式(GB/T 7714):
Song Lina,Qiao Guanglei,Xu Yingjie,et al.Role of non-coding RNAs in cardiotoxicity of chemotherapy[J].SURGICAL ONCOLOGY-OXFORD.2018,27(3):526-538.doi:10.1016/j.suronc.2018.06.003.
APA:
Song, Lina,Qiao, Guanglei,Xu, Yingjie,Ma, Lijun&Jiang, Weihua.(2018).Role of non-coding RNAs in cardiotoxicity of chemotherapy.SURGICAL ONCOLOGY-OXFORD,27,(3)
MLA:
Song, Lina,et al."Role of non-coding RNAs in cardiotoxicity of chemotherapy".SURGICAL ONCOLOGY-OXFORD 27..3(2018):526-538