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EAACI Position paper on the standardization of nasal allergen challenges

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收录情况： ◇ SCIE

作者：
Auge, J.[1,2] * ; Vent, J.[1,2,18] * ; Agache, I.[27] ; Airaksinen, L.[3] ; Campo Mozo, P.[19] ; Chaker, A.[4] ; Cingi, C.[5] ; Durham, S.[6] ; Fokkens, W.[7] ; Gevaert, P.[8] ; Giotakis, A.[9] ; Hellings, P.[10] ; Herknerova, M.[11] ; Hox, V.[10] ; Klimek, L.[12] ; La Melia, C.[13] ; Mullol, J.[14,15,16] ; Muluk, N. B.[28] ; Muraro, A.[17] ; Naito, K.[29] ; Pfaar, O.[12,18] ; Riechelmann, H.[9] ; Rondon, C.[19] ; Rudenko, M.[20] ; Samolinski, B.[21] ; Tasca, I.[13] ; Tomazic, P.[22] ; Vogt, K.[23] ; Wagenmann, M.[24] ; Yeryomenko, G.[25] ; Zhang, L.[26] ; Moesges, R.[2,*1] ;
机构： [1]Univ Cologne, Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Cologne, Germany [2]Univ Cologne, Inst Med Stat & Computat Biol, Fac Med, Cologne, Germany [3]Finnish Inst Occupat Hlth, Hlth & Work Abil, Helsinki, Finland [4]Tech Univ Munich, Klinikum Rechts Isar, Ctr Allergy & Environm ZAUM, Dept Otolaryngol, Munich, Germany [5]Eskisehir Osmangazi Univ, ENT Dept, Fac Med, Eskisehir, Turkey [6]Imperial Coll, NHLI, Allergy & Clin Immunol, London, England [7]Acad Med Ctr, Otorhinolaryngol, Amsterdam, Netherlands [8]Univ Ghent, Otorhinolaryngol, Ghent, Belgium [9]Med Univ Innsbruck, Dept Otorhinolaryngol Head & Neck Surg, Innsbruck, Austria [10]Clin Univ St Luc, Dept Otorhinolaryngol, Brussels, Belgium [11]Nemocnice Homolce, Alergol & Klin Imunol, Prague, Czech Republic [12]Ctr Rhinol & Allergol, Wiesbaden, Germany [13]Azienda Ausl Imola, Dept ENT, Imola, Italy [14]Inst Invest Biomed August Pi & Sunyer IDIBAPS, Clin & Expt Immunoallergy, Barcelona, Spain [15]Univ Barcelona, Hosp Clin Barcelona, Dept ORL, Barcelona, Spain [16]Ctr Invest Biomed Red Enfermedades Resp CIBERES, Barcelona, Spain [17]Padua Gen Univ Hosp, Referral Ctr Food Allergy, Dept Pediat, Padua, Italy [18]Heidelberg Univ, Med Fac Mannheim, Univ Med Mannheim, Dept Otorhinolaryngol Head & Neck Surg, Mannheim, Germany [19]IBIMA Reg Univ Hosp Malaga, Allergy Unit, ARADyAL, Malaga, Spain [20]London Allergy & Immunol Ctr, London, England [21]Med Univ Warsaw, Dept Prevent Envinronm Hazards & Allergol, Warsaw, Poland [22]Med Univ Graz, Dept Gen Otorhinolaryngol Head & Neck Surg, Graz, Austria [23]Univ Latvia, Fac Med, Riga, Latvia [24]Dusseldorf Univ Hosp UKD, Dept Otorhinolaryngol, Dusseldorf, Germany [25]Kharkiv Natl Med Univ, Kharkov, Ukraine [26]Capital Med Univ, Beijing TongRen Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China [27]Transylvania Univ Brasov, Fac Med, Dept Allergy & Clin Immunol, Brasov, Romania [28]Kirikkale Univ, Fac Med, Dept Otorhinolaryngol, Kirikkale, Turkey [29]Fujita Hlth Univ, Otolaryngol, 1-98 Denngakugakubo,Kutukake Cho, Toyoake, Aichi, Japan
出处：
DOI： 10.1111/all.13416
ISSN：

关键词： allergic rhinitis diagnostic tools nasal allergen challenge nasal provocation test

摘要：
Nasal allergen challenge (NAC) is an important tool to diagnose allergic rhinitis. In daily clinical routine, experimentally, or when measuring therapeutic success clinically, nasal allergen challenge is fundamental. It is further one of the key diagnostic tools when initiating specific allergen immunotherapy. So far, national recommendations offered guidance on its execution; however, international divergence left many questions unanswered. These differences in the literature caused EAACI to initiate a task force to answer unmet needs and find a consensus in executing nasal allergen challenge. On the basis of a systematic review containing nasal allergen challenges of the past years, task force members reviewed evidence, discussed open issues, and studied variations of several subjective and objective assessment parameters to propose a standardized way of a nasal allergen challenge procedure in clinical practice. Besides an update on indications, contraindications, and preparations for the test procedure, main recommendations are a bilaterally challenge with standardized allergens, with a spray device offering 0.1mL per nostril. A systematic catalogue for positivity criteria is given for the variety of established subjective and objective assessment methods as well as a schedule for the challenge procedure. The task force recommends a unified protocol for NAC for daily clinical practice, aiming at eliminating the previous difficulty of comparing NAC results due to unmet needs.

基金：
EAACI
语种：
外文
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被引次数：
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中科院(CAS)分区：
出版当年[2017]版：
大类 | 1 区 医学
小类 | 1 区 过敏 2 区 免疫学
最新[2023]版：
大类 | 1 区 医学
小类 | 1 区 免疫学 2 区 过敏
JCR分区：
出版当年[2016]版：
Q1 IMMUNOLOGY Q1 ALLERGY
最新[2023]版：
Q1 IMMUNOLOGY Q1 ALLERGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2016版] 出版当年五年平均 出版前一年[2015版] 出版后一年[2017版]

第一作者：
第一作者机构： [1]Univ Cologne, Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Cologne, Germany [2]Univ Cologne, Inst Med Stat & Computat Biol, Fac Med, Cologne, Germany
共同第一作者：
通讯作者：
通讯机构： [2]Univ Cologne, Inst Med Stat & Computat Biol, Fac Med, Cologne, Germany [*1]Institute of Medical Statistics and Computational Biology, Faculty of Medicine, University of Cologne, Cologne, Germany.
推荐引用方式(GB/T 7714)：
Auge J.,Vent J.,Agache I.,et al.EAACI Position paper on the standardization of nasal allergen challenges[J].ALLERGY.2018,73(8):1597-1608.doi:10.1111/all.13416.
APA：
Auge, J.,Vent, J.,Agache, I.,Airaksinen, L.,Campo Mozo, P....&Moesges, R..(2018).EAACI Position paper on the standardization of nasal allergen challenges.ALLERGY,73,(8)
MLA：
Auge, J.,et al."EAACI Position paper on the standardization of nasal allergen challenges".ALLERGY 73..8(2018):1597-1608

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