机构：[1]Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China临床科室耳鼻咽喉-头颈外科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Ministry of Education, Beijing Institute of Otorhinolaryngology, Beijing, China研究所耳鼻咽喉科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院[3]Beijing Key Laboratory of Head and Neck Molecular Diagnostic Pathology, Beijing, China
Background: Narrow band imaging (NBI) and stroboscopy are non-invasive techniques to detect the malignant lesions of the vocal cord. This study was to assess the diagnostic value of combined endoscopic analysis in the applanate indiscernible early-stage vocal cord cancer. Methods: A total of 110 patients with 160 suspicious vocal cord malignant lesions were included in this retrospective study. Stroboscopy was immediately performed after NBI and white light endoscopy (WLE) were performed in all patients. Excisional biopsy was performed to examine histopathology examination. Results: We found that the diagnostic specificity and PPV were higher in the NBI and WLE combined with stroboscopy group than in the NBI and WLE group without stroboscopy (88.9% vs 72.5%, 88.4% vs 60.9%). However, the diagnostic sensitivity was not significantly different in those two groups (69.3% vs 67.7%). Conclusion: NBI and WLE combined with stroboscopy is a promising method to detect early-stage vocal cord cancer with the advantage of clinical feasibility and diagnostic specificity.
基金：
National Natural Science
Foundation of China (Grant No. 81473499), the Beijing Municipal
Administration of Hospitals Clinical Medicine Development of special
funding support (Grant No. XM201311) and Beijing Municipal
Science & Technology Commission Program (Grant No.
Z141107002514003)
第一作者机构：[1]Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China
通讯作者：
通讯机构：[1]Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China[2]Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Ministry of Education, Beijing Institute of Otorhinolaryngology, Beijing, China[*1]Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
推荐引用方式(GB/T 7714)：
Yang Yifan,Fang Jugao,Zhong Qi,et al.The value of narrow band imaging combined with stroboscopy for the detection of applanate indiscernible early-stage vocal cord cancer[J].ACTA OTO-LARYNGOLOGICA.2018,138(4):400-406.doi:10.1080/00016489.2017.1388542.
APA：
Yang, Yifan,Fang, Jugao,Zhong, Qi,Xu, Wen,Ma, Hongzhi...&Hou, Lizhen.(2018).The value of narrow band imaging combined with stroboscopy for the detection of applanate indiscernible early-stage vocal cord cancer.ACTA OTO-LARYNGOLOGICA,138,(4)
MLA：
Yang, Yifan,et al."The value of narrow band imaging combined with stroboscopy for the detection of applanate indiscernible early-stage vocal cord cancer".ACTA OTO-LARYNGOLOGICA 138..4(2018):400-406
