机构:[1]Medical Physics Department, Health Science Center of Peking University, Beijing 100191, China[2]Beijing City Key Laboratory of Medical Physics and Engineering, Peking University, Beijing 100871, China[3]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing 100005, China研究所眼科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院[4]Department of Neuroscience Charleston, Medical University of South Carolina, SC 29425, USA[5]Basic Medical College, Hebei North University, Zhangjiakou 050024, China[6]Medical Physics, Department of Radiology, University Medical Center Freiburg, Freiburg 79106, Germany.
The binocular disparity of two retina images is a main cue of stereoscopic vision. However, the global dependency between brain response and binocular disparity still remains unclear. Here, we used functional Magnetic Resonance Imaging (fMRI) to identify stereopsis-related brain regions with a modified Random Dot Stereogram (RDS) and plotted the activation variation curves under different disparity size. In order to eliminate the confounding shape difference between the stereogram and the plane, commonly seen in RDS, we modified the RDS to a checkerboard version. We found that V3A, V7 and MT+/V5 in dorsal visual stream were activated in stereoscopic experiment, while little activation was found in ventral visual regions. According to the activation trends, 13 subjects were divided into three groups: 5 subjects with turning points (a shift from increased to decreased activation), 5 subjects without turning points and 3 subjects with activation unrelated to disparity. We inferred that the dorsal visual stream primarily processes spatial depth information, rather than shape information. (C) 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
基金:
Beijing Natural Science Foundation
(7162112) and the National Natural Science Foundation of China
(81171330).
第一作者机构:[1]Medical Physics Department, Health Science Center of Peking University, Beijing 100191, China[2]Beijing City Key Laboratory of Medical Physics and Engineering, Peking University, Beijing 100871, China
通讯作者:
通讯机构:[1]Medical Physics Department, Health Science Center of Peking University, Beijing 100191, China[2]Beijing City Key Laboratory of Medical Physics and Engineering, Peking University, Beijing 100871, China[*1]Medical Physics Department, Health Science Center of Peking University, Beijing 100191, China
推荐引用方式(GB/T 7714):
Wang Fei,Yang Wenchao,Zhang Li,et al.Brain activation difference evoked by different binocular disparities of stereograms: An fMRI study[J].PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS.2016,32(10):1308-1313.doi:10.1016/j.ejmp.2016.07.007.
APA:
Wang, Fei,Yang, Wenchao,Zhang, Li,Gundran, Andrew,Zhu, Xun...&Gao, Song.(2016).Brain activation difference evoked by different binocular disparities of stereograms: An fMRI study.PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS,32,(10)
MLA:
Wang, Fei,et al."Brain activation difference evoked by different binocular disparities of stereograms: An fMRI study".PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS 32..10(2016):1308-1313