Purpose:To assess whether anterior corneal curvature radius (CCR) is associated with the increased prevalence of myopia in Asia.Methods:The investigation included the adult populations of the Central India Eye and Medical Study (CIEMS; 4711 adults) and Beijing Eye Study (BES; 3468 adults) and the children and teenager populations of the Shandong Children Eye Study (6026 children; age: 9.7 3.3 years; range: 4-18 years) and Beijing Pediatric Eye Study (681 children; age: 7.7 1.6 years; range: 5-13 years).Results:In both adult study populations, CCR was not significantly (BES: P = 0.60; CIEMS: P = 0.14) associated with the level of education. In highly myopic subgroups, longer CCR was associated with a lower educational level [CIEMS: P = 0.04; standardized regression coefficient = -0.23; nonstandardized regression coefficient B: -0.06; 95% confidence interval (CI), -0.11 to 0.01] or showed a tendency toward a lower educational level (BES: P = 0.09; = -0.25; B: -0.06; 95% CI, -0.12 to 0.01). In the young study populations, longer CCR was significantly associated with parameters indicating a lower educational level, such as lower educational level of father (P = 0.001; : -0.04; B: -0.01; 95% CI, -0.02 to -0.01) and mother (P = 0.0.02; : -0.14; B: -0.05; 95% CI, -0.09 to -0.01) and more time spent outdoors (P = 0.001; : 0.15; B: 0.05; 95% CI, 0.02 to 0.07) and less time spent indoors (P < 0.001; : -0.15; B: -0.04; 95% CI, -0.06 to -0.02). In all study populations, longer CCR was significantly correlated (multivariate analysis) with longer axial length and lower prevalence of high myopia.Conclusions:Adult study populations and schoolchildren populations did not differ in the associations of longer CCR with parameters indicating a lower educational level, longer axial length, and lower prevalence of high myopia. CCR was not useful for the differentiation between high myopia in schoolchildren and high pathological myopia in adults.
基金:
State Natural Sciences FundNational Natural Science Foundation of China (NSFC) [81041018]; Natural Sciences Fund of Beijing government [7092021, 7112031]; Shandong Science & Technology Department [2011GGB14097, 2011GGH21835, 2012YD18081]; Shandong Health Department [2011HD014]; Jinan Science & Technology Bureau [201102061]; Grants-in-Aid for Scientific ResearchMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of ScienceGrants-in-Aid for Scientific Research (KAKENHI) [15H04993] Funding Source: KAKEN
第一作者机构:[1]Capital Med Univ, Beijing Inst Ophthalmol, Beijing Ophthalmol & Visual Sci Key Lab, Beijing Tongren Eye Ctr,Beijing Tongren Hosp, Beijing, Peoples R China[2]Heidelberg Univ, Med Fac Mannheim, Dept Ophthalmol, Mannheim, Germany
通讯作者:
通讯机构:[5]Capital Med Univ, Beijing Tongren Hosp, Beijing Tongren Eye Care Ctr, Beijing, Peoples R China[*1]Beijing Tongren Hosp, Beijing Tongren Eye Ctr, 1 Dong Jiao Min Lane, Beijing 100730, Peoples R China
推荐引用方式(GB/T 7714):
Jonas Jost B.,Bi Hong Sheng,Wu Jian Feng,et al.Corneal Curvature Radius in Myopia of Schoolchildren Versus Adult Myopia[J].CORNEA.2016,35(10):1333-1337.doi:10.1097/ICO.0000000000000854.
APA:
Jonas, Jost B.,Bi, Hong Sheng,Wu, Jian Feng,Xu, Liang,Wang, Ya Xing...&Panda-Jonas, Songhomitra.(2016).Corneal Curvature Radius in Myopia of Schoolchildren Versus Adult Myopia.CORNEA,35,(10)
MLA:
Jonas, Jost B.,et al."Corneal Curvature Radius in Myopia of Schoolchildren Versus Adult Myopia".CORNEA 35..10(2016):1333-1337