机构:[1]Department of Ophthalmology, Chinese PLA General Hospital, Beijing 100853, China[2]Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing 100730, China研究所眼科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Purpose. To determine the repeatability of recalculated corneal visualization Scheimpflug technology (CorVis ST) parameters and to study the variation of biomechanical properties and their association with demographic and ocular characteristics. Methods. A total of 783 healthy subjects were included in this study. Comprehensive ophthalmological examinations were conducted. The repeatability of the recalculated biomechanical parameters with 90 subjects was assessed by the coefficient of variation (CV) and intraclass correlation coefficient (ICC). Univariate and multivariate linear regression models were used to identify demographic and ocular factors. Results. The repeatability of the central corneal thickness (CCT), deformation amplitude (DA), and first/second applanation time (A1/A2-time) exhibited excellent repeatability (CV% <= 3.312% and ICC >= 0.929 for all measurements). The velocity in/out (V-in/out), highest concavity- (HC-) radius, peak distance (PD), and DA showed a normal distribution. Univariate linear regression showed a statistically significant correlation between V-in, V-out, DA, PD, and HC- radius and IOP, CCT, and corneal volume, respectively. Multivariate analysis showed that IOP and CCT were negatively correlated with V-in, DA, and PD, while there was a positive correlation between V-out and HC- radius. Conclusion. The ICCs of the recalculated parameters, CCT, DA, A1-time, and A2-time, exhibited excellent repeatability. IOP, CCT, and corneal volume significantly influenced the biomechanical properties of the eye.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81271052]; priming scientific research foundation for the junior researcher in Beijing Tongren Hospital, Capital Medical University [2015-YJJ-ZZL-008]; Beijing Key Laboratory of Ophthalmology and Visual Science [2016YKSJ02]
语种:
外文
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2015]版:
大类|3 区生物
小类|3 区生物工程与应用微生物4 区医学:研究与实验
最新[2025]版:
大类|4 区医学
小类|4 区生物工程与应用微生物4 区医学:研究与实验
JCR分区:
出版当年[2014]版:
Q3BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q3BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
第一作者机构:[1]Department of Ophthalmology, Chinese PLA General Hospital, Beijing 100853, China
通讯作者:
推荐引用方式(GB/T 7714):
Wu Ying,Tian Lei,Huang Yi-fei.In Vivo Corneal Biomechanical Properties with Corneal Visualization Scheimpflug Technology in Chinese Population[J].BIOMED RESEARCH INTERNATIONAL.2016,2016:doi:10.1155/2016/7840284.
APA:
Wu, Ying,Tian, Lei&Huang, Yi-fei.(2016).In Vivo Corneal Biomechanical Properties with Corneal Visualization Scheimpflug Technology in Chinese Population.BIOMED RESEARCH INTERNATIONAL,2016,
MLA:
Wu, Ying,et al."In Vivo Corneal Biomechanical Properties with Corneal Visualization Scheimpflug Technology in Chinese Population".BIOMED RESEARCH INTERNATIONAL 2016.(2016)