机构：[1]University Hospital[2]MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc – Roussillon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France[3]INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, Paris, France[4]Department of Clinical Epidemiology and Biostatistics and Medicine, McMaster University, Hamilton, ON, Canada[5]Center for Research in Health Technologies and Information Systems – CINTESIS,Universidade do Porto, Porto, Portugal[6]Department of Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland[7]Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium[8]Allergy and Respiratory Diseases Clinic, DIMI, University of Genoa, IRCCS AOU San Martino-IST, Genoa, Italy[9]Division of Allergy/Immunology, University of South Florida, Tampa, FL, USA[10]ProAR – Nucleo de Excelencia em Asma, Federal University of Bahia, Bahia, Brasil[11]Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France[12]EPAR U707 INSERM, Paris, France[13]Laboratory of Clinical Immunology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium[14]Vilnius University Clinic of Children’s Diseases, Vilnius, Lithuania[15]Sachs’ Children’s Hospital, Stockholm, Sweden[16]Department of Dermatology and Allergy, Charite – Universit€atsmedizin Berlin, Berlin, Germany[17]Woolcock Institute of Medical Research, University of Sydney and Sydney Local Health District, Glebe, NSW, Australia[18]Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Denmark[19]Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, The Netherlands[20]Latvian Association of Allergists, Center of Tuberculosis and Lung Diseases of Latvia, Riga, Latvia[21]Department of Paediatrics, Oslo University Hospital, Oslo, Norway[22]Unitat de Rinologia i Clınica de l’Olfacte, Servei d’ORL, Hospital Clınic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Catalonia, Spain[23]Food Allergy Referral Centre Veneto Region, Department of Women and Child Health, Padua General University Hospital, Padua, Italy[24]EFA European Federation of Allergy and Airways Diseases Patients’ Associations, Brussels, Belgium[25]Center for Pediatrics and Child Health, Institute of Human Development, Royal Manchester Children’s Hospital, University of Manchester, Manchester[26]General Practitioner, Woodbrook Medical Centre, Loughborough, UK[27]Department of Lung Diseases and Clinical Allergology, University of Turku, Turku, Finland[28]Department of Pulmonology, Celal Bayar University, Manisa, Turkey[29]Department of Dermatology, Medical University of Graz, Graz, Austria[30]Transylvania University Brasov, Brasov, Romania[31]Department of Clinical Research Center, International University of Health and Welfare/Sanno Hospital, Tokyo, Japan[32]Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland[33]Department of Allergy and Immunology, Hospital Quiro´n Bizkaia, Erandio, Spain[34]Centre for Research in Environmental Epidemiology, Barcelona, Spain[35]Hospital del Mar Research Institute, Barcelona, Spain[36]CIBER Epidemiologı´a y Salud Pu´blica, Barcelona, Spain[37]Department of Experimental and Health Sciences, University of Pompeu Fabra, Barcelona, Spain[38]Digi Health, Montpellier, France[39]David Hide Asthma and Allergy Research Centre, Isle of Wight, UK[40]EuroAsian Respiratory Society, Astana City, Kazakhstan[41]Faculdade de Medicina de Lisboa, Portuguese National Programme for Respiratory Diseases, Lisbon, Portugal[42]Department of Medicine, University of Cape Town, Cape Town, South Africa[43]Section of Respiratory Disease, Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy[44]Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands[45]Service de Pneumologie IV, Hoˆpital Abderrahman Mami, Ariana, Tunisie[46]Department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh[47]Centre for Individualized Medicine, Department of Pediatrics, Faculty of Medicine, Linko¨ping University, Linko¨ping, Sweden[48]Deputy National Medical Director, NHS England, England, UK[49]Department of Dermatology and Allergy, Rheinische Friedrich-Wilhelms-University Bonn, Bonn, Germany[50]Department of Respiratory Medicine and Allergology, University Hospital, Lund, Sweden[51]Department of Geriatrics, Montpellier University Hospital[52]EA 2991 Movement To Health, Euromov, University Montpellier, Montpellier, France[53]Pediatric Department, University of Verona Hospital, Verona, Italy[54]Que´bec Heart and Lung Institute, Laval University, Que´bec City, QC, Canada[55]Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome[56]Second University of Naples and Institute of Translational Medicine, Italian National Research Council, Naples, Italy[57]Allergist, La Rochelle[58]Directeur Ge´ne´ral Adjoint, Montpellier University Hospital, Montpellier, France[59]Health Economics and Health Technology Assessment, Institute of Health & Wellbeing, University of Glasgow, Glasgow[60]Institute of Lung Health, Respiratory Biomedical Unit, University Hospitals of Leicester NHS Trust, Leicestershire, UK[61]Universita¨tsmedizin der Johannes Gutenberg-Universita¨t Mainz, Mainz, Germany[62]National Heart and Lung Institute, Imperial College[63]Imperial College and Royal Brompton Hospital, London, UK[64]Centro Medico Docente La Trinidad, CaRacas, Venezuela[65]Imperial College London – National Heart and Lung Institute, Royal Brompton Hospital NHS, London, UK[66]Federal University of Minas Gerais, Medical School, Department of Pediatrics, Belo Horizonte, Brazil[67]Assitant Director General, Montpellier, France[68]Department of Paediatrics, Oslo University Hospital and University of Oslo, Oslo, Norway[69]Allergy and Asthma Associates of Southern California, Mission Viejo, CA, USA[70]Allergy and Immunology Laboratory, Metropolitan University, Simon Bolivar University, Barranquilla, Colombia[71]Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands[72]Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece[73]National Cooperative Group of Paediatric Research on Asthma, Asthma Clinic and Education Center of the Capital Institute of Pediatrics, Peking and Center for Asthma Research and Education, Beijing, China首都儿科研究所[74]Chachava Clinic, David Tvildiani Medical University-AIETI Medical School, Grigol Robakidze University, Tbilisi, Georgia[75]Pulmonolory Research Institute FMBA, Moscow, Russia[76]Medicine Department, IRCCS-Azienda Ospedaliera Universitaria San Martino, Genoa, Italy[77]Latvian Association of Allergists, University Children Hospital of Latvia, Riga, Latvia[78]Life and Health Sciences Research Institute, ICVS, School of Health Sciences, University of Minho, Braga, Portugal[79]Department of Medicine, Nova Southeastern University, Davie, FL, USA[80]European Innovation Partnership on Active and Healthy Ageing, Reference Site, NHS Scotland, Glasgow[81]Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, UK[82]The Centre for Allergy Research, The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden[83]Department of Dermatology and Allergy, Technische Universita¨t Ma¨nchen, Munich, Germany[84]Allergy Division, Chest Disease Department, University Hospital of Strasbourg, Strasbourg, France[85]European Regional and Local Health Association, Brussels, Belgium[86]Allergology and Immunology Discipline, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania[87]Department of Medicine, Division of Clinical Immunology and Allergy, McMaster University, Hamilton, ON, Canada[88]Laboratoire de Pharmacologie Respiratoire UPRES EA220, Hoˆpital Foch, Suresnes Universite´ Versailles Saint-Quentin, Versailles Saint-Quentin[89]Respiratory Diseases Department, Rangueil-Larrey Hospital, Toulouse[90]Service de physiologie, Hoˆpital Cochin, Universite´ Paris-Descartes, Assistance publique-Hoˆpitaux de Paris, Paris, France[91]Medical Faculty Skopje, University Clinic of Pulmology and Allergy, Skopje, R. Macedonia[92]Service de Pneumo-Allergologie, CentreHospitalo-Universitaire de Be´ni-Messous, Algers, Algeria[93]Ecole des Mines, Ale` s, France[94]Medical Faculty, Vilnius University, Vilnius, Lithuania[95]Allergy and Clinical Immunology Section, National Heart and Lung Institute, Imperial College London, London, UK[96]Section of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, MI, USA[97]Pediatric Allergy and Immunology Unit, Ain Shams University, Cairo, Egypt[98]Clinic of Children’s Diseases, Faculty of Medicine, Vilnius University, Vilnius, Lithuania[99]Global Allergy and Asthma Platform GAAPP, Vienna, Austria[100]Education for Health, Warwick, UK[101]Allergy Department, The Bambino Gesu` Children’s Research Hospital Holy see[102]Department of Epidemiology, Regional Health Service Lazio Region, Rome, Italy[103]National Center for Disease Control and Public Health of Georgia, Tbilisi, Georgia[104]Turkish Thoracic Society Asthma-Allergy Working Group, Kocaeli, Turkey[105]Allergy and Immunology Division, Clinica Ricardo Palma, Lima, Peru[106]Sociedad Latinoamericana de Allergia, Asma e Immunologia, Mexico City, Mexico[107]Center of Allergy and Immunology, Georgian Association of Allergology and Clinical Immunology, Tbilisi, Georgia[108]Faculty of the Department of Neurology, University of Washington School of Medicine, Seattle, WA, USA[109]Immunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile[110]Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland[111]Department of Respiratory Diseases, Odense University Hospital, Odense, Denmark[112]Institute of Epidemiology I, German Research Centre for Environmental Health, Helmholtz Zentrum Mu¨nchen, Neuherberg, Germany[113]Vienna Challenge Chamber, Vienna, Austria[114]Department of Paediatrics and Child Health, University College Cork, Cork, Ireland[115]University of Southampton Faculty of Medicine, University Hospital Southampton, Southampton, UK[116]Universite´ Paris-Sud, Le Kremlin Biceˆtre, France[117]School of Psychology, Plymouth University, Plymouth, UK[118]Servicio de Alergia e Immunologia, Clinica Santa Isabel[119]Libra Foundation, Buenos Aires, Argentina[120]Airway Disease Infection Section, National Heart and Lung Institute, Imperial College, London, UK[121]Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium[122]Medical Commission, Montpellier University Hospital, Montpellier, France[123]Hallym University College of Medicine, Hallym University Sacred Heart Hospital, Gyeonggi-do, South Korea[124]Allergology Department, Centre de l’Asthme et des Allergies. Hoˆpital d’Enfants Armand-Trousseau, Paris, France[125]Ukrainian Medical Stomatological Academy, Poltava, Ukraine[126]Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine[127]School of Medicine, Department of Chest Diseases, Immunology and Allergy Division, Hacettepe University, Ankara, Turkey[128]Institute of Social Medicine, Epidemiology and Health Economics, Charite´ – Universita¨tsmedizin Berlin, Berlin, Germany[129]Department of Medicine, McMaster University, Health Sciences Centre 3V47, Hamilton, ON, Canada[130]GARD Chairman, Geneva, Switzerland[131]Center for Rhinology and Allergology, Wiesbaden, Germany[132]Socie´te´ de Pneumologie de Langue Franc¸ aise et Espace Francophone de Pneumologie, Paris, France[133]Department of Respiratory Medicine, Faculty of Medicine and Dentistry, University Hospital Olomouc, Olomouc, Czech Republic[134]Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children’s Hospital, GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands[135]Department of Immunology, Rheumatology and Allergy, Medical University of Lodz[136]Division of Internal Medicine, Asthma and Allergy, KUNA, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland[137]Pulmonology and Allergology Center, Vilnius University, Vilnius, Lithuania[138]VIB Inflammation Research Center, Ghent University, Ghent, Belgium[139]Department for Pediatric Pneumology and Immunology, Charite´ Medical University, Berlin, Germany[140]Clı´nica de Alergia, Asma y Pediatrı´a, Hospital Me´dica Sur, Me´ xico City, Me´ xico[141]University of Medicine and Pharmacy, Hochiminh City, Vietnam[142]Departments of Internal Medicine and Pediatrics (Divisions of Allergy and Immunology), University of Tennessee College of Medicine, Germantown, TN, USA[143]Scottish Centre for Respiratory Research, Cardiovascular & Diabetes Medicine, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee, UK[144]State Key Laboratory of Respiratory Diseases, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China[145]Department of Pulmonary Medicine, CHU Sart-Tilman, Liege, Belgium[146]Service de Pneumo-allergologie, Hoˆpital Saint-Joseph, Paris[147]Service de Pneumologie, University of Nantes, UMR INSERM, UMR1087/CNR 6291, l’Institut du Thorax, Nantes, France[148]Department of Pulmonary Medicine, Rashid Hospital, Dubai, UAE[149]Department of Respiratory Medicine, University Hospital, Bratislava, Slovakia[150]Department of Medicine (RCSI), Bon Secours Hospital, Glasnevin, Dublin, Ireland[151]Kronikgune, Basque Region, Spain[152]Division of Clinical Immunology and Allergy, Laboratory of Behavioral Immunology Research, The University of Mississippi Medical Center, Jackson, MS, USA[153]Respiratory Disease Research, Shahid Beheshti University of Medical Sciences, Tehran, Iran[154]Allergie-Centrum-Charite´ at the Department of Dermatology and Allergy, Charite´ – Universita¨tsmedizin Berlin, Berlin, Germany[155]Department of Paediatrics, Maputo Central Hospital, Maputo, Mozambique[156]Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden[157]Allergy and Asthma Medical Group and Research Center, San Diego, CA, USA[158]Hautklinik – Klinik fu¨r Dermatologie & Allergologie, Universita¨tsklinikum der RWTH Aachen, Aachen, Deutschland[159]Croatian Pulmonary Society, Zagreb, Croatia[160]National Institute of Pneumology M. Nasta, Bucharest, Romania[161Faculty of Medicine, University of Belgrade, Belgrade, Serbia[162]National Center for Research in Chronic Respiratory Diseases, Tishreen University School of Medicine, Latakia, Syria[163]De´partement de Pharmacologie, CHU de Bordeaux, Universite´ Bordeaux, INSERM U657, Bordeaux Cedex[164]Department of Public Health and Biostatistics, Paris Descartes University[165]Paris Municipal Department of Social Action, Childhood and Health, Paris, France[166]Aura Andalucia, Jaen, Spain[167]Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisboa, Portugal[168]Institute of Medical Statistics, Informatics and Epidemiology, Medical Faculty, University of Cologne, Cologne, Germany[169]Scientific Centre of Children’s Health under the Russian Academy of Medical Sciences, Moscow, Russia[170]Section of Otolaryngology-Head and Neck Surgery, The University of Chicago Medical Center and The Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA[171]Hospital de Nin˜ os Orlando Alassia, Santa Fe, Argentina[172]Hospital of the Hospitaller Brothers in Buda, Budapest, Hungary[173]Pediatric Pneumology and Immunology, Charite´ Universita¨tsmedizin Berlin, Berlin, Germany[174]ENT Department, University Hospital of Kinshasa, Kinshasa, Congo[175]Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Vic., Australia[176]National Hospital Organization, Tokyo National Hospital, Tokyo[177]Depatment of Otorhinolaryngology, Chiba University Hospital, Chiba[178]Depatment of Otolaryngology, Nippon Medical School, Tokyo, Japan[179]1Centre Hospitalier Universitaire Pe´diatrique Charles de Gaulle, Ouagadougou, Burkina Faso[180]Cardio-Thoracic and Vascular Department, University Hospital of Pisa, Pisa, Italy[181]Dept. of ComparativeMedicine, Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University and University Vienna, Vienna, Austria[182]Department of Immunology and Allergology, Faculty of Medicine and Faculty Hospital in Pilsen, Charles University in Prague, Pilsen, Czech Republic[183]Respiratory Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy[184]Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, South Korea[185]Nuffield Department of Medicine, University of Oxford, Oxford, UK[186]Department of Pediatrics, Nippon Medical School, Tokyo, Japan[187]Center for Rhinology and Allergology, Wiesbaden, Germany[188]Conseil Ge´ne´ral de l’Economie. Ministe`re de l’Economie, de l’Industrie et du Nume´rique, Paris, France[189]De´partement de pe´diatrie, CHU de Grenoble, Grenoble cedex 9, France[190]Children’s Hospital Srebrnjak, Zagreb, School of Medicine, University J.J. Strossmayer, Osijek, Croatia[191]Karl Landsteiner Institute for Clinical and Experimental Pneumology, Hietzing Hospital, Vienna, Austria[192]Clinic of Allergy & Asthma, Medical University Sofia, Sofia, Bulgaria[193]Department of Pulmonary Medicine and Tuberculosis, GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands[194]Allergy Diagnostic and Clinical Research Unit, University of Cape Town Lung Institute, Cape Town, South Africa[195]Academic Centre of Primary Care, University of Aberdeen, Aberdeen, UK[196]LungenClinic Grosshansdorf, Airway Research Center North, Member of the German Center for Lung Research, Grosshansdorf, Germany[197]Conseil De´partemental de l’Ordre des Pharmaciens, Maison des Professions Libe´rales, Montpellier, France[198]SLAAI, Mexico City, Mexico[199]Allergy and Clinical Immunology Department, Hospitais da Universidade de Coimbra, Coimbra, Portugal[200]Association Asthme et Allergie, Paris, France[201]Servic¸o de Imunoalergologia, Hospital da Luz, Lisboa, Portugal[202]Polibienestar Research Institute, University of Valencia, Valencia[203]Primary Care Respiratory Research Unit, Institutode Investigacio´n Sanitaria de Palma IdisPa, Palma de Mallorca, Spain[204]Allergy Unit, Complesso Integrato Columbus, Rome, Italy[205]Hospital de Clinicas, University of Parana, Parana, Brazil[206]Department of Allergy, Asthma and Immunology, Children’s Mercy Hospitals and Clinics and Pediatrics and Medicine University of Misouri-Kansas City School of Medicine, Kansas City, MI, USA[207]Division of Allergy Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel[208]Allergy and Clinical Immunology Department, Centro Me´dicoDocente la, Trinidad, Venezuela[209]The Royal National TNE Hospital, University College London, London, UK[210]Otolaryngology and Head & Neck Surgery, CHU Rangueil-Larrey, Toulouse, France[211]Allergy Unit, Department of Dermatology, University Hospital of Zurich, Zu¨rich, Switzerland[212]Allergy and Respiratory Research Group, Medical School, Centre for Population Health Sciences, The University of Edinburgh, Edinburgh, UK[213]Department of Pediatrics & Child Health, Department of Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada[214]Sociedad Paraguaya de Alergia Asma e Inmunologıa, Paraguay, Paraguay[215]Julius Center of Health Sciences and Primary Care, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands[216]Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of Sa˜o Paulo, Sa˜o Paulo, Brazil[217]Kyrgyzstan National Centre of Cardiology and Internal medicine, Euro-Asian respiratory Society, Bishkek, Kyrgyzstan[218]Pulmonary Division, Heart Institute (InCor), Hospital da Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil[219]European Union GeriatricMedicine Society, Vienna, Austria[220]Department of Epidemiology, CAPHRI School of Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands[221]Centre of Pneumology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal[222]Division of Allergy and Clinical Immunology, University of Salerno, Salerno, Italy[223]Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria[224]Pneumology and Allergy Department, Hospital Clı´nic, Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, Barcelona, Spain[225]Clinical Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institutet and University Hospital, Stockholm, Sweden[226]Department of Chest Medicine, Centre Hospitalier Universitaire Dinant-Godinne, Universite´ Catholique de Louvain, Yvoir, Belgium[227]Pulmonary Unit, Department of Cardiology, Thoracic and Vascular Medicine, Arcispedale S.Maria Nuova/IRCCS, Research Hospital, Reggio Emilia, Italy[228]Division of Allergy and Immunology, Department of Pediatrics, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, Thailand[229]Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Italy[230Department of Otorhinolaryngology, HNO-Klinik, Universita¨tsklinikum Du¨ sseldorf, Du¨ sseldorf, Germany[231]Asthma UK, London, UK[232]Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore City, Singapore[233]Eshelman School of Pharmacy, University of North Carolina, Chapel HillNC[234]Bradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UJ[235]Department of Research, Olmsted Medical Center, Rochester, MN, USA[236]Cyprus International Institute for Environmental & Public Health in Association with Harvard School of Public Health, Cyprus University of Technology, Limassol, Cyprus[237]The Allergy and Asthma Institute, Islamabad, Pakistan[238]Department of Paediatrics and Child Health, Red Cross Children’s Hospital, MRC Unit on Child & Adolescent Health, University of Cape Town, Cape Town, South Africa[239]Universidad Cato´lica de Co´rdoba, Co´rdoba, Argentina[240]Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China临床科室耳鼻咽喉-头颈外科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[241]University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia[242]Vice President for Research, University Montpellier, Montpellier[243]UVSQ, UMR-S 1168, Universite´ Versailles St-Quentin-en-Yvelines, Paris, France[244]Allergy Unit, Instituto CUF Porto e Hospital CUF Porto[245]Health Information and Decision Sciences Department – CIDES, Faculdade de Medicina, Universidade do Porto[246]Faculdade de Medicina da Universidade do Porto, Porto, Portugal[247]GARD Executive Committee, Bahia, Brasil[248]EPAR UMR-S UPMC, Paris, France[249]Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden[250]Member of the Global Allergy and Asthma European Network (GA2LEN)[251]Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway[252]Allergy Department, 2nd Pediatric Clinic, Athens General Children’s Hospital “P&A Kyriakou”, University of Athens, Athens, Greece[253]Honorary Clinical Research Fellow, Allergy and Respiratory Research Group, The University of Edinburgh, Edinburgh[254]Department of Infection, Immunity and Inflammation, University of Leicester, Leicester[255]Wellcome Centre for Global Health, Imperial College[256]MRC-PHE Centre for Environment and Health, Imperial College, London, UK[257]Re´gion Languedoc Roussillon, Roussillon, France[258]SLaai, Sociedad Latinoamericana de Allergia, Asma e Immunologia, Barranquilla, Colombia[259]GARD Executive Committee, Moscow, Russia[260]ZAUMCenter for Allergy and Environment, Helmholtz Center Munich, Technische Universita¨t Mu¨nchen, Munich, Germany[261]Service de Pneumologie, Hoˆpital Biceˆtre, Inserm UMR_S999, Le Kremlin Biceˆtre, France[262]MRC & Asthma UK Centre in Allergic Mechanisms ofAsthma, London, UK[263]Sorbonne Universite´ s, UPMC Univ Paris 06, UMR_S 1136, Institut Pierre Louis d’Epide´miologie et de Sante´ Publique, Equipe EPAR, Paris, France[264]Institute for Clinical Epidemiology and Biometry, University of Wuerzburg, Wuerzburg, Germany[265]Serbian Association for Asthma and COPD, Belgrade, Serbia[266]Department of Immunology, Monash University, Melbourne, Vic., Australia[267]Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University and University Vienna, Vienna, Austria[268]Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty Mannheim, Universita¨tsmedizin Mannheim, Heidelberg University, Mannheim, Germany[269]Research in Real-Life, Cambridge, UK[270]Department of Medicine, Christian Albrechts University, Airway Research Center North, Member of the German Center for Lung Research, Kiel, Germany[271]Clı´nica El Avila, 6a transversal Urb, Caracas, Venezuela[272]Regional Agency for Health and Social Care, Reggio Emilia[273]CNR Institute of Biomedicine and Molecular Immunology “A. Monroy”, Palermo, Italy[274]Department of Pediatrics, Hospital “Archbishop Makarios III”, Nicosia, Cyprus[275]Centre for Health Economics, University of York, York, UK
Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for integrated care pathways, innovation in clinical trials and, above all, patient empowerment. MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) is a simple system centred around the patient which was devised to fill many of these gaps using Information and Communications Technology (ICT) tools and a clinical decision support system (CDSS) based on the most widely used guideline in allergic rhinitis and its asthma comorbidity (ARIA 2015 revision). It is one of the implementation systems of Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA). Three tools are used for the electronic monitoring of allergic diseases: a cell phone-based daily visual analogue scale (VAS) assessment of disease control, CARAT (Control of Allergic Rhinitis and Asthma Test) and e-Allergy screening (premedical system of early diagnosis of allergy and asthma based on online tools). These tools are combined with a clinical decision support system (CDSS) and are available in many languages. An e-CRF and an e-learning tool complete MASK. MASK is flexible and other tools can be added. It appears to be an advanced, global and integrated ICT answer for many unmet needs in allergic diseases which will improve policies and standards.
基金：
ChiesiChiesi Pharmaceuticals Inc; GSKGlaxoSmithKline; Cipla; Sanofi/RegeneronRegeneron; NovartisNovartis; Circassia; MerckMerck & Company; Stallergenes; Medical Research CouncilUK Research & Innovation (UKRI)Medical Research Council UK (MRC)European Commission; JP Moulton Charitable Foundation; North West Lung Research Centre Charity; European UnionEuropean Commission; National Institute of Health ResearchNational Institute for Health Research (NIHR); Thermo Fisher; AstraZenecaAstraZeneca; ALK; GlaxoSmithKlineGlaxoSmithKline; ALK Abello; Merck USAMerck & Company; Biomay; Leti; Biotech Tools; A. MenariniMenarini Group; Aerocrine; Merck Sharp DohmeMerck & Company; TevaTeva Pharmaceutical Industries; Boehringer IngelheimBoehringer Ingelheim; MSD; OrionPharma; Centocor; Sanofi Pasteur; Grunenthal; Synairgen; Stallergens; ALK Abello (Germany/Denmark); Allergopharma (Germany); Stallergenes (Germany/France); HAL Allergy (Germany/the Netherlands); Artu Biologicals (the Netherlands)Netherlands Government; Allergy Therapeutics/Bencard (UK/Germany); Hartington (Spain); Lofarma (Italy); Novartis/Leti (Germany/Spain); GlaxoSmithKline (UK/Germany); Essex Pharma (Germany); Cytos (Switzerland); Curalogic (Denmark); Roxall (Germany); Biomay (Austria); Thermo Fisher (Germany); Circassia (UK); Biotech Tools s.a. (Belgium); Meda Pharma GmbH (Germany); HAL Allergy (the Netherlands/Germany); Meda (Germany/Sweden); Dutch Lung Foundation; Ubbo Emmius Foundation; Stichting Astma Bestrijding; Adamed; Allergopharma; AlmirallAlmirall; Celon PharmaDexcel Pharma; FAES; HALHorticulture Australia Limited; Meda; PfizerPfizer; Polfarmex; Polpharma; Stallergen; Lekam; UCBUCB Pharma SA; Sanofi; Carnot; Senosiain; Almirral; Jansen; PearlLuxembourg National Research Fund; RocheRoche Holding; AZ; AstellasAstellas Pharmaceuticals; GenentechRoche HoldingGenentech; Uriach; Abbott LaboratoriesAbbott Laboratories; ALK-Abello; Ohropax; ServierServier; Stada; MenariniMenarini Group; Allergy Therapeutics; BayerBayer AG; Johnson+ JohnsonJohnson & JohnsonJohnson & Johnson USA; Arthrocare; Bencard; BiotechTools; Lofarma; Ursapharm; Bitop; AIPreven; Optima; Torii Co. Ltd.; Shionogi Co. Ltd.; MSD Co. LtD; Tanabe-Mitsubishi; Ono; Taiho; Torii; Kyowa-Kirin; Guidotti-Malesci; Mundipharma; TakedaTakeda Pharmaceutical Company Ltd; Zambon; Chiesi FarmaceuticiChiesi Pharmaceuticals Inc; Merck Sharp DohmeMerck & Company; DGAKI; GlaxoSmithKline (Germany)GlaxoSmithKline; Bencard (Germany); Novartis (Germany)Novartis; Ministry of Science, Education and Sports of Republic of CroatiaMinistry of Science, Education and Sports, Republic of Croatia; SandozNovartis; Salveo; Schering-PloughMerck & CompanySchering Plough Corporation; UK National Health Service; British Lung Foundation; AKL Ltd; Eli LillyEli Lilly; Napp; Orion; Respiratory Effectiveness Group; Zentiva; Efficacy and Mechanism Evaluation programme; HTA; Novartis Farma; Faes Farma; Bial AristeguiBial Group; BoehringerBoehringer Ingelheim; Biomay AG; Vienna, Austria; Uppsala, Sweden; Medical Research CouncilUK Research & Innovation (UKRI)Medical Research Council UK (MRC)European Commission [MR/K006665/1] Funding Source: researchfish; Asthma UK [AUK-AC-2012-01, CH11SJ] Funding Source: researchfish; MRCUK Research & Innovation (UKRI)Medical Research Council UK (MRC) [MR/K006665/1] Funding Source: UKRI
第一作者机构：[1]University Hospital[2]MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc – Roussillon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France[3]INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, Paris, France[243]UVSQ, UMR-S 1168, Universite´ Versailles St-Quentin-en-Yvelines, Paris, France[*1]CHRU Montpellier, 34295 Montpellier Cedex 5, France.
通讯作者：
通讯机构：[1]University Hospital[2]MACVIA-LR, Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc – Roussillon, European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France[3]INSERM, VIMA: Ageing and Chronic Diseases, Epidemiological and Public Health Approaches, Paris, France[243]UVSQ, UMR-S 1168, Universite´ Versailles St-Quentin-en-Yvelines, Paris, France[*1]CHRU Montpellier, 34295 Montpellier Cedex 5, France.
推荐引用方式(GB/T 7714)：
J. Bousquet,H. J. Schunemann,J. Fonseca,et al.MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation[J].ALLERGY.2015,70(11):1372-1392.doi:10.1111/all.12686.
APA：
J. Bousquet,H. J. Schunemann,J. Fonseca,B. Samolinski,C. Bachert...&J. Mercier.(2015).MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation.ALLERGY,70,(11)
MLA：
J. Bousquet,et al."MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation".ALLERGY 70..11(2015):1372-1392
医学