机构:[1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing, China首都医科大学附属北京同仁医院临床科室眼科亦庄院区医学视光科[2]Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China首都医科大学附属北京同仁医院研究所眼科研究所[3]Anyang Eye Hospital, Anyang, Henan Province, China[4]Department of Epidemiology and Health Statistics, Peking University School of Public Health, Beijing, China[5]Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, University of Sydney, Sydney, Australia
PURPOSE. To investigate whether time outdoors and a range of other activities are associated with change in spherical equivalent (SE) and axial length in Chinese children over a period of 2 METHODS. A total of 1997 children aged 12.7 +/- 0.5 (10.9-15.6) years in the Anyang Childhood Eye Study (ACES) were examined annually (baseline and two follow-up visits). Myopia was defined as cycloplegic SE < -0.50 diopters (D). Questionnaires were administered to the students and parents at baseline to gauge time spent outdoors and on other tasks. We ran mixed linear models including age, sex, and years of follow-up. RESULTS. In the full cohort of children there was a suggestive association between time spent outdoors and change in axial length; however, the effect size was very small (high versus low tertile: -0.016 mm/y, P = 0.053). The association was observed in children not myopic at baseline (high versus low tertile, -0.036 mm/y; P = 0.009) but not in those already myopic at baseline (high versus low tertile: -0.005 mm/y; P = 0.595). Time outdoors and change in SE showed similar, but nonsignificant, relationships (P > 0.05), perhaps due to insufficient statistical power. The other activities examined and parental myopia were not associated with changes in SE and axial length (P > 0.11). CONCLUSIONS. Within the normal range of variation encountered in these Chinese children, a wide range of activities were largely unrelated to myopia progression at this age. However, there was suggestive evidence that greater time outdoors was associated with slower axial elongation in nonmyopic teenagers, but not in existing myopes.
基金:
Major State Basic Research Development Program
of China (973 Program, 2011CB504601) of the Ministry of Science
and Technology, the Major International (Regional) Joint Research
Project of the National Natural Science Foundation of China
(81120108007), Beijing Nova Program (Z121107002512055), and
the National Natural Science Foundation of China (81300797).
第一作者机构:[1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing, China[2]Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China
通讯作者:
通讯机构:[1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing, China[2]Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China[*1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing, China .Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China, 100730
推荐引用方式(GB/T 7714):
Li Shi-Ming,Li He,Li Si-Yuan,et al.Time Outdoors and Myopia Progression Over 2 Years in Chinese Children: The Anyang Childhood Eye Study[J].INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE.2015,56(8):4734-4740.doi:10.1167/iovs.14-15474.
APA:
Li, Shi-Ming,Li, He,Li, Si-Yuan,Liu, Luo-Ru,Kang, Meng-Tian...&for the Anyang Childhood Eye Study Group.(2015).Time Outdoors and Myopia Progression Over 2 Years in Chinese Children: The Anyang Childhood Eye Study.INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,56,(8)
MLA:
Li, Shi-Ming,et al."Time Outdoors and Myopia Progression Over 2 Years in Chinese Children: The Anyang Childhood Eye Study".INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 56..8(2015):4734-4740