We welcome the letters of Chantada et al1 and Wallang and
Rath2 that clarify the important points of our article.3 We agree
that delay in timing of removal of eyes with International Intraocular Retinoblastoma Classification4 (IIRC) group E is the key
element associated with significant incidence of lethal outcome.
In all children, the delay arose because pre-enucleation chemotherapy was given.
第一作者机构：[1]Princess Margaret Hosp, Ontario Canc Inst, Campbell Family Inst Canc Res, Univ Hlth Network, Toronto, ON M4X 1K9, Canada[2]Hosp Sick Children, Toronto, ON M5G 1X8, Canada[3]Univ Toronto, Toronto, ON, Canada
推荐引用方式(GB/T 7714)：
Gallie Brenda L.,Chan Helen S. L.,Dimaras Helen,et al.Does Pre-Enucleation Chemotherapy Lead to Increased Risk of Metastasis in Advanced Retinoblastoma? Reply[J].JOURNAL OF CLINICAL ONCOLOGY.2011,29(24):3335-3336.doi:10.1200/JCO.2011.36.3549.
APA：
Gallie, Brenda L.,Chan, Helen S. L.,Dimaras, Helen&Zhao, Junyang.(2011).Does Pre-Enucleation Chemotherapy Lead to Increased Risk of Metastasis in Advanced Retinoblastoma? Reply.JOURNAL OF CLINICAL ONCOLOGY,29,(24)
MLA：
Gallie, Brenda L.,et al."Does Pre-Enucleation Chemotherapy Lead to Increased Risk of Metastasis in Advanced Retinoblastoma? Reply".JOURNAL OF CLINICAL ONCOLOGY 29..24(2011):3335-3336
医学