1. Introduction Rhinoscleroma is a chronic granulomatous, slowly progressive infection that affects the nose and other respiratory tract structures. It was first described in 1870 by dermatologist Ferdinando Von Hebra and posteriorly named respiratory scleroma, which emphasizes involvement of upper and lower airways [1]. It occurs frequently in the nasal fossae, eventually extending itself to the larynx, the rhinopharynx, the mouth and the paranasal sinuses; the lips, trachea, and bronchi may also be affected to a lesser degree. Extrarespiratory involvement has rarely been described. Scleroma is endemic in some Central American countries, Indonesia, India, Poland, Hungary, Russia, and some African countries. In China the frequency of this disease is low. The regions of endemicity is Shandong province. The infection is due to a capsulate gram-negative bacterium, Klebsiella rhinoscleromatis, which was first described by Von Frisch in 1882 [2].