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Rhinofacial conidiobolomycosis caused by Conidiobolus coronatus in a Chinese rice farmer

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机构: [1]Juntendo Univ Nerima Hosp, Dept Dermatol & Allergol, Nerima Ku, Tokyo 1170033, Japan [2]Capital Univ Med Sci, Tong Ren Hosp, Dept Dermatol, Beijing, Peoples R China [3]Capital Univ Med Sci, Tong Ren Hosp, Dept Pathol, Beijing, Peoples R China [4]Capital Univ Med Sci, Tong Ren Hosp, Dept Otorhinolaryngol, Beijing, Peoples R China [5]Capital Univ Med Sci, Tong Ren Hosp, Dept Clin Lab, Beijing, Peoples R China [6]Meiji Pharmaceut Univ, Dept Microbiol, Tokyo, Japan [7]Juntendo Univ Sch Med, Dept Dermatol, Bunkyo Ku, Tokyo, Japan
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P>We provide the first report of rhinofacial conidiobolomycosis caused by Conidiobolus coronatus in China. The patient was a 36-year-old male rice farmer from Jiang Xi province who presented with diffuse swelling with classical centrofacial distribution and involvement of the right paranasal sinuses. Histopathology showed granulomas with hyphae surrounded by an eosinophilic sheath (Splendore-Hoeppli phenomenon). Culture of biopsy specimens on Sabouraud's dextrose agar led to the growth of fungi with microscopically visible conidiophores and terminal spherical conidia (primary conidium), with multiple secondary conidia and villose conidia. The patient was successfully treated with combination therapy, primarily itraconazole and terbinafine. We conclude with a brief literature review of the epidemiology of conidiobolomycosis.

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出版当年[2009]版:
大类 | 4 区 医学
小类 | 4 区 皮肤病学 4 区 真菌学
最新[2025]版:
大类 | 2 区 医学
小类 | 2 区 皮肤病学 2 区 真菌学
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出版当年[2008]版:
Q3 DERMATOLOGY Q3 MYCOLOGY
最新[2023]版:
Q1 DERMATOLOGY Q2 MYCOLOGY

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第一作者机构: [2]Capital Univ Med Sci, Tong Ren Hosp, Dept Dermatol, Beijing, Peoples R China
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