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Audiological Results in a Group of Children with Auditory Neuropathy Spectrum Disorder

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收录情况： ◇ SCIE

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机构： [1]Key Laboratory and Department of Otolaryngology, Head and Neck Surgery, [2]Department of Radiology,Beijing Institute of Otolaryngology and Beijing Tongren Hospital, Capital Medical University, Beijing , PR China

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关键词： Auditory neuropathy Auditory neuropathy spectrum disorder Click auditory brainstem responses Cochlear microphonics Cochlear nerve deficiency Distortion product otoacoustic emissions

摘要：

Objective: To enrich clinical information of auditory neuropathy spectrum disorder. Methods: Forty-eight infants and young children with severely abnormal auditory brainstem responses (ABRs) along with preserved distortion product otoacoustic emissions (DPOAEs) and/or cochlear microphonics (CMs) were included in this retrospective study. Click ABRs, CMs, DPOAEs, behavioral thresholds and tympanograms were established. Results: Audiological information of 88 ears (40 cases were bilateral and 8 unilateral) that met the inclusion criteria were analyzed. Most of the ears (68.2%) had absent click ABRs at the maximum presentation level of 100 dB nHL, while other ears had repeatable wave V with lowest thresholds of 80 dB nHL. Behavioral hearing of 23 cases ranged from mild (n = 1), moderate (n = 2) to severe and profound loss (n = 20). CMs were present in all ears in spite of those with middle ear pathology, while DPOAEs were present only in 40% of the affected ears. Conclusion: Diverse results of audiological assessments are shown in this group of children. Concurrent pathologies may make auditory neuropathy spectrum disorder undetected. Absent or severely abnormal ABR along with present CMs are the most reliable measures for detecting this disorder at this stage. Copyright (C) 2010 S. Karger AG, Basel

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出版当年[2009]版：

大类 | 4 区医学

小类 | 4 区耳鼻喉科学

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无

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出版当年[2008]版：

Q3 OTORHINOLARYNGOLOGY

最新[2023]版：

无

影响因子： 0 最新[2023版] 0 最新五年平均 1.024 出版当年[2008版] 0.9 出版当年五年平均 0.757 出版前一年[2007版] 1 出版后一年[2009版]

第一作者：

第一作者机构： [1]Key Laboratory and Department of Otolaryngology, Head and Neck Surgery,

通讯作者：

通讯机构： [1]Key Laboratory and Department of Otolaryngology, Head and Neck Surgery, [*1]Key Laboratory and Department of Otolaryngology, Head and Neck Surgery No. 17, HouGouHuTong, DongCheng District Beijing 100005 (PR China)

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