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Combined mycophenolate mofetil and minimal dose calcineurin inhibitor in stable liver transplant patients is nephro- and hepatoprotective

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收录情况: ◇ SCIE ◇ CPCI(ISTP)

机构: [1]Univ Hosp, Dept Gen Visceral & Transplantat Surg, Essen, Germany [2]Univ Hosp, Dept Gastroenterol & Hepatol, Essen, Germany [3]Capital Univ Med Sci, Beijing Tongren Hosp, Dept Surg, Beijing, Peoples R China
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摘要:
Background: Calcineurin inhibitor (CNI)-related nephrotoxicity significantly contributes to chronic renal failure after liver transplantation (LT). Methods: In this prospective study, LT patients with renal dysfunction were randomized to either receive mycophenolate mofetil (MMF) followed by stepwise reduction of CNI with defined minimal CNI-trough levels (MMF group) or to continue their maintenance CNI dose (control group). Immune monitoring was performed in a subgroup of the patients.

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中科院(CAS)分区:
出版当年[2007]版:
大类 | 2 区 医学
最新[2023]版:
大类 | 1 区 医学
小类 | 1 区 胃肠肝病学
JCR分区:
出版当年[2006]版:
Q1 GASTROENTEROLOGY & HEPATOLOGY
最新[2023]版:
Q1 GASTROENTEROLOGY & HEPATOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2006版] 出版当年五年平均 出版前一年[2005版] 出版后一年[2007版]

第一作者:
第一作者机构: [1]Univ Hosp, Dept Gen Visceral & Transplantat Surg, Essen, Germany [2]Univ Hosp, Dept Gastroenterol & Hepatol, Essen, Germany
通讯作者:
通讯机构: [1]Univ Hosp, Dept Gen Visceral & Transplantat Surg, Essen, Germany [2]Univ Hosp, Dept Gastroenterol & Hepatol, Essen, Germany
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