B-type natriuretic peptides are predominantly synthesized in the ventricular myocytes. This is the response to volume overload or increased stress to the ventricular watt. plasma B-type natriuretic peptide Levels are elevated in patients with chronic renal failure due to reduced glomerular filtration and/or increased myocardial biosynthesis. Allograft renal transplantation significantly reduces plasma B-type natriuretic peptide. Our previous clinical observations have demonstrated that acute allograft renal rejection is associated with a sudden increase in plasma B-type natriuretic peptides. We hypothesized that plasma B-type natriuretic peptide may be used as a sensitive and specific biomarker for clinical diagnosis of acute allograft renal rejection. (C) 2007 Elsevier Ltd. All rights reserved.
第一作者机构：[1]Zhengzhou Univ, Affiliated Hosp 1, Dept Emergency Med, Zhengzhou, Henan Province, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Sun Tong-Wen,Zhang Shou-Yan,Wang Le-Xin.Plasma B-type natriuretic peptide for early diagnosis of allograft rejection after renal transplantation[J].MEDICAL HYPOTHESES.2008,70(6):1160-1162.doi:10.1016/j.mehy.2007.03.045.
APA：
Sun, Tong-Wen,Zhang, Shou-Yan&Wang, Le-Xin.(2008).Plasma B-type natriuretic peptide for early diagnosis of allograft rejection after renal transplantation.MEDICAL HYPOTHESES,70,(6)
MLA：
Sun, Tong-Wen,et al."Plasma B-type natriuretic peptide for early diagnosis of allograft rejection after renal transplantation".MEDICAL HYPOTHESES 70..6(2008):1160-1162
