高级检索
当前位置: 首页 > 详情页

Vogt-Koyanagi-Harada disease and fungal meningitis.

文献详情

资源类型:
Pubmed体系:
机构: [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China [2]Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Sciences Key Laboratory [3]Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China [3]Department of Ophthalmology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Ruprecht- Karls-University Heidelberg, Mannheim, Germany
出处:
ISSN:

摘要:
To describe a patient who initially presented with features of Vogt-Koyanagi-Harada disease and who eventually demonstrated symptoms of mycotic meningitis.An 18-year-old immunocompetent boy showed a disseminated uveitis with patchy thickening of the posterior choroid. A clinical neurologic examination and a microbiological assessment revealed neck stiffness as well as pleocytosis, increased protein content, a decreased concentration of glucose and chloride, and cryptococcal fungi in the cerebrospinal fluid. It led to the diagnosis of cryptococcal meningitis.Antifungal therapy was initiated and given for 2 months. After bilateral retrobulbar injections of 2.5 mg of dexamethasone and 20 mg of triamcinolone acetonide, choroidal edema regressed and visual acuity increased from 0.4 to 1.0 at 3 weeks after start of therapy. Microbiological examination of cerebrospinal fluid samples taken 30 days later was unremarkable. Ophthalmoscopy showed some fine pigment clumping and depigmentation in the macula.According to the International Nomenclature Committee for Vogt-Koyanagi-Harada diagnosis, the patient was diagnosed with incomplete Vogt-Koyanagi-Harada because he had not suffered any ocular trauma, had not undergone ocular surgery, and presented with bilateral multifocal choroiditis accompanied by signs of meningitis without skin abnormalities. Because skin changes can occur months to years after the initial symptoms, the patient may eventually fulfill the criteria for complete Vogt-Koyanagi-Harada disease.

基金:
语种:
PubmedID:
第一作者:
第一作者机构: [1]Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
通讯作者:
通讯机构: [2]Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Sciences Key Laboratory [*1]Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Hospital, 1 Dong Jiao Min Xiang, Dong Cheng District, 100730 Beijing, China
推荐引用方式(GB/T 7714):
APA:
MLA:

资源点击量:21169 今日访问量:0 总访问量:1219 更新日期:2025-01-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学附属北京同仁医院 技术支持:重庆聚合科技有限公司 地址:北京市东城区东交民巷1号(100730)