机构：[1]Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.临床科室内分泌科首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.
Aims: Neck circumference (NC) was found to be related to the risk factors for coronary heart disease (CHD). However, the effects of NC on CHD are still controversial. To evaluate the relationship between NC and CHD, a meta-analysis of observational studies was performed. Method: Eligible studies on the association between NC and CHD were searched in Medline, Embase, Ovid, and Web of Science databases published in English from January 1980 to December 2016. Moreover, studies published in Chinese in Wanfang and China Hospital Knowledge databases were also searched. Random effects models in the metafor package in statistical analysis software R 3.3.3 were used for the meta-analysis. Heterogeneity was analyzed with Q statistics. Results: Eight studies were selected for the meta-analysis. A larger NC was associated with a higher prevalence of CHD (OR = 1.18, 95% CI 1.04-1.34, p = 0.0108). The eight studies were further divided into three subgroups according to the criteria for diagnosing CHD. In the subgroup of coronary angiography, NC was also found to be associated with the prevalence of CHD with low heterogeneity (OR = 1.17, 95% CI 1.07-1.28, p = 0.0007, I 2 = 17.02%). However, in the subgroup of computed tomography or past history, no association between NC and CHD was found. In addition, subgroup analyses were also conducted according to the regions of the study. No association between NC and CHD was identified in either Chinese studies or Brazil studies (OR = 1.20, 95% CI 0.96-1.49; OR = 1.31, 95% CI 0.82-2.09, respectively). Conclusion: Larger NC is associated with increased risk of CHD, especially when coronary angiography was taken to diagnose CHD.
基金：
Capital’s Funds
for Health Improvement and Research [2016-2-2054],
and the Beijing Municipal Training Foundation for
Highly-qualified and Technological Talents of Health
System [2014-3-013]. Dr. Li’s, Dr. Zand’s, Mr. Fogg’s,
and Dr. Dye’s time is supported by the University of
Rochester’s Clinical and Translational Science Award
(CTSA) number UL1 TR000042 and UL1 TR002001
from the National Center for Advancing Translational
Sciences of the National Institutes of Health. Dr. Zand
is also supported by the National Institute of Allergy
and Infectious Diseases and the National Institute of
Immunology, grant numbers AI098112 and AI069351
语种：
外文
PubmedID：
第一作者：
第一作者机构：[1]Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.[2]Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.[*1]Department of Endocrinology Beijing Tongren Hospital, Capital Medical University, Beijing, China
通讯作者：
通讯机构：[1]Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.[2]Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.[*1]Department of Endocrinology Beijing Tongren Hospital, Capital Medical University, Beijing, China[*2]Clinical and Translational Science Institute, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA
推荐引用方式(GB/T 7714)：
Yang Guang-Ran,Dye Timothy D,Zand Martin S,et al.Association Between Neck Circumference and Coronary Heart Disease: A Meta-analysis.[J].Asian/Pacific Island nursing journal.2019,4(1):34-46.doi:10.31372/20190401.1031.
APA：
Yang Guang-Ran,Dye Timothy D,Zand Martin S,Fogg Thomas T,Yuan Shen-Yuan...&Li Dongmei.(2019).Association Between Neck Circumference and Coronary Heart Disease: A Meta-analysis..Asian/Pacific Island nursing journal,4,(1)
MLA：
Yang Guang-Ran,et al."Association Between Neck Circumference and Coronary Heart Disease: A Meta-analysis.".Asian/Pacific Island nursing journal 4..1(2019):34-46
