机构：[1]Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China.[2]Eye Diseases and Optometry Institute, Beijing 100044, China.[3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.[4]College of Optometry, Peking University Health Science Center, Beijing 100044, China.
To assess the association between endogenous cortisol level and the risk of central serous chorioretinopathy (CSC).Case-control studies were systematically searched on PubMed, Embase, Cochrane, China National Knowledge Infrastructure (CNKI) for publishes between January 1990 and July 2017 to assess the association between endogenous cortisol level and CSC. The main endpoints were serum cortisol level at 8 a.m. and 24-hour urine 17-hydroxysteroids level. We assessed pooled data using a random-effects model.Of 86 identified studies, 5 were eligible included in our analysis. The 5 studies included a total of 315 participants, of whom 187 had CSC. Statistically significant association was observed between serum cortisol level (summary SMD=0.77, 95%CI=0.55-0.99), 24-hour urine 17-hydroxysteroids level (summary SMD=0.95, 95%CI=0.61-1.30), and the risk of CSC.Endogenous cortisol level is associated with an increased risk of CSC. Combined treatment targeting the serum cortisol level at 8 a.m. and 24-hour urine 17-hydroxysteroids level can be a potential preventive strategy for individuals who are at risk of CSC and therapeutic strategy for patients with CSC.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2017]版：
大类|4 区医学
小类|4 区眼科学
最新[2025]版：
大类|4 区医学
小类|3 区眼科学
第一作者：
第一作者机构：[1]Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China.[2]Eye Diseases and Optometry Institute, Beijing 100044, China.[3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.[4]College of Optometry, Peking University Health Science Center, Beijing 100044, China.
通讯作者：
通讯机构：[1]Department of Ophthalmology, Peking University People's Hospital, Beijing 100044, China.[2]Eye Diseases and Optometry Institute, Beijing 100044, China.[3]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing 100044, China.[4]College of Optometry, Peking University Health Science Center, Beijing 100044, China.[*1]Department of Ophthalmology and Visual Sciences，Peking University People’s Hospital，Beijing 100044，China．
推荐引用方式(GB/T 7714)：
Liang Zhi-Qiao,Huang Lyu-Zhen,Qu Jin-Feng,et al.Association between endogenous cortisol level and the risk of central serous chorioretinopathy: a Meta-analysis.[J].International Journal of Ophthalmology.2018,11(2):296-300.doi:10.18240/ijo.2018.02.19.
APA：
Liang Zhi-Qiao,Huang Lyu-Zhen,Qu Jin-Feng&Zhao Ming-Wei.(2018).Association between endogenous cortisol level and the risk of central serous chorioretinopathy: a Meta-analysis..International Journal of Ophthalmology,11,(2)
MLA：
Liang Zhi-Qiao,et al."Association between endogenous cortisol level and the risk of central serous chorioretinopathy: a Meta-analysis.".International Journal of Ophthalmology 11..2(2018):296-300
