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Type 2 choroidal neovascularisation in polypoidal choroidal vasculopathy: a retrospective case series.

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机构： [1]Department of Ophthalmology, Peking University People's Hospital, Beijing, China. [2]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China. [3]Collage of Optometry, Peking University health Science Center, Beijing, China. [4]Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.

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To demonstrate the coexistence of polypoidal choroidal vasculopathy (PCV) with type 2 neovascularisation (NV), we used multimodal imaging, including spectral-domain optical coherence tomography angiography (SD-OCTA), to identify both types of lesions in the same eye.This retrospective case series reviewed patients with PCV diagnosed with indocyanine green angiography (ICGA), fluorescein angiography (FA), SD-OCT and SD-OCTA.15 eyes of 14 patients were imaged and diagnosed with PCV by ICGA. ICGA identified polyps in all these eyes, while SD-OCTA imaging identified polypoidal lesions in only 11 (73%) of these eyes with PCV. Branching vascular networks (BVNs) were detected in 12 eyes (80%) by ICGA and SD-OCTA. Type 2 NV was detected in four eyes (27%) by FA and SD-OCTA. In these eyes, a combination of polyps, BVNs and type 2 NV were detected using FA, ICGA and SD-OCTA.BVN and type 2 NV can coexist in the same PCV eye and communicate with each other. This suggests that polyps may represent a structural variant of neovascular tissue rather than a distinct pathogenic process in NV.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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出版当年[2017]版：

大类 | 3 区医学

小类 | 2 区眼科学

最新[2025]版：

大类 | 2 区医学

小类 | 2 区眼科学

第一作者：

第一作者机构： [1]Department of Ophthalmology, Peking University People's Hospital, Beijing, China. [2]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China. [3]Collage of Optometry, Peking University health Science Center, Beijing, China.

通讯作者：

通讯机构： [1]Department of Ophthalmology, Peking University People's Hospital, Beijing, China. [2]Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, Beijing, China. [3]Collage of Optometry, Peking University health Science Center, Beijing, China. [*1]Department of Ophthalmology, Peking University People’s Hospital, Beijing 100044, China

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