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Roles of CD43, CD20 and local IgE in the pathogenesis of nasal polyps

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收录情况: ◇ 北大核心 ◇ 中华系列

机构: [1]Beijing Institute of Otorhinolaryngology, Beijing 100005, China. wangxiangdong88@sina.com
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To estimate the roles of CD43, CD20 and total IgE in the pathogenesis of nasal polyps.Twenty-six cases of nasal polyps and 20 cases of mucosa of middle turbinates were used in present study.The number of CD43+ cells, CD20+ cells and plasma cells in nasal polyps were significantly more than that in middle turbinates (P < 0.01). The positive rate of local IgE+ cells in nasal polyps was significantly higher than in middle turbinate (P < 0.01).There were active cellular immunity and humoral immunity in nasal polyps. Local allergy may play a role in the pathogenesis of nasal polyps.

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第一作者机构: [1]Beijing Institute of Otorhinolaryngology, Beijing 100005, China. wangxiangdong88@sina.com
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