机构:[1]Beijing Institute of Ophthalmology, Beijing 100005, China.研究所眼科研究所首都医科大学附属北京同仁医院首都医科大学附属同仁医院
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摘要:
To study the inhibitory role of taurine on H(2)O(2)-induced bovine lens epithelial cell apoptosis.By terminal deoxyribonucleotide transferase-mediated dUTP nick end labeling (TUNEL) detection and bovine lens organ culture, we examined the affect of taurine on the number of H(2)O(2)-induced bovine lens epithelial cells with apoptosis, the related comparisons and statistic analyses were carried out.(1) Lens epithelial cell apoptosis began before lens opaqueness (lens became opaque after 6 hours of incubation, while the lens epithelial cell apoptosis was detected after 3 hours of incubation); (2) Taurine could apparently inhibit H(2)O(2)-induced bovine lens epithelial cell apoptosis.Taurine has an inhibitory role on H(2)O(2)-induced bovine lens epithelial cell apoptosis and can delay and ameliorate the occurrence and development of cataract.
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中文
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第一作者机构:[1]Beijing Institute of Ophthalmology, Beijing 100005, China.
推荐引用方式(GB/T 7714):
Chen F,Chen C.An experimental research of taurine on H2O2-induced bovine lens epithelial cell apoptosis[J].Chinese Journal of Ophthalmology.2000,36(4):272-4, 17.